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Bellinzona buy marijuana
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Several studies showed cannabinoids action on CB1 and CB2 receptors reduces the hyperalgesic phase in inflammatory pain, leading to an improvement of conditions. The active compounds of these galenic preparations show a high variability making titration mandatory. For this reason, the exact oil composition knowledge is fundamental for personalizing therapy. This amis at adapting the correct dose to the patient, improving safety and efficacy of the galenic formulation, choosing the best preparation for each patient. Purpose: The aim of this study was to investigate oil preparations variability among different galenic laboratories in order to highlight the importance of titration activity. Methods: Cannabis pharmacological active compounds titration has been performed in a large cohort of galenic laboratories in Italy. Results: A number of samples of Cannabis oil from 83 pharmacies between January and February were evaluated. Moreover, seasonal variability in analytes concentrations was observed. Conclusion: This study described a wide range of oily samples from a large number of galenic laboratories, compared to published papers. In conclusion, knowledge of the exact oil composition is fundamental in the perspective of personalized therapy. Further studies aiming at the correlation between galenic composition and cannabinoids pharmacokinetics, clinical outcomes and toxic effects could be useful to improve our knowledge. Substances Analgesics Cannabinoids Dronabinol.
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