Barbiturates

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Barbiturates are synthetic drugs used in medicine to depress the central nervous system. The effects range from mild sedation to coma and they may be used a sedatives, hypnotics or as part of anesthesia. Some barbiturates are used to relieve tension or anxiety prior to surgery. Barbiturates used to be regularly prescribed to treat insomnia, depression and anxiety, but the small difference between a normal dose and an overdose led to a number of accidental deaths, as well as people using them to commit suicide. Therefore, the use of barbiturates as sedatives or hypnotics to relieve insomnia or daytime restlessness caused by everyday stresses is no longer advised and has been replaced with safer medicines. Today, they are generally only used to treat extreme and serious cases of insomnia. They are also used to help control seizures in epilepsy and some are used as an adjunct to anesthesia. Pharmacological barbiturates are based on the parent compound barbituric acid. The type of barbituate depends on the substituent used at position 5 of this basic skeleton. Around different types of barbiturates have been synthesized since , when barbital, the first pharmacologically active form, was synthesized. However only around 50 of these agents have ever been used in medicine. They are available in the following forms. For supply, the maximum penalty is 14 years in prison and a fine. If barbiturates are prepared as injection drugs, they are then classified as class A drugs and the penalties for possession and supply are more severe. Barbiturates slow down the CNS in a similar way to alcohol and depending on how rapidly they produce effects and the duration of those effects, they may be classed as ultra-short-, short-, intermediate- or long-acting. The effects of Intermediate-acting barbiturates such as butabarbital sodium last for between 6 and 12 hours and these are used to treat insomnia. Pentobarbital is an example of a short-acting barbituate used to help patients fall asleep. The ultra-short acting thiamylal is administered as an injection to induce unconsciousness patients about to undergo surgery. Gaseous anesthetics are then used to maintain the unconsciousness throughout the surgical procedure. Small does of barbiturates make people feel relaxed, uninhibited, mildly euphoric, free of anxiety and sleepy. Larger doses can cause hostility, anxiety, body ataxia, slurred speech, paranoia and suicidal thoughts. The risk of falling over or having an accident is also increased. With prolonged use, tolerance can quickly develop, meaning larger does than the original dose are then required to produce the same effects. This can increase the risk of overdose, signs of which include shallow breathing, rapid and weak pulse, dilated pupils, clammy skin, coma and even death as a result of the central nervous system and respiratory system become severely depressed. Since tolerance and physical dependence can develop with p prolonged use of barbiturates, withdrawal from regular use can lead to various problems including the following:. In cases where a person withdraws from regular use of very high doses, symptoms can be more severe and include the following:. Sudden withdrawal from the regular use of high doses can be fatal and for individuals who have become addicted to barbiturates it is essential that they seek the care of trained rehabilitation professionals to help them withdraw safely and effectively. Cancel reply to comment. There are about 77, people known to have cystic fibrosis. The accepted number, at the moment, is about 80, Force microscopy is a technique which would probably be best described with the help of a small finger with an apex just a few atoms in size that can touch objects. This is a learning finger. Autism is a clinical diagnosis. There is no one test to diagnose autism. Depending on the type of medical professional diagnosing, typically the DSM-V standard classification of mental disorders used by mental health professionals in the U. This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. By Sally Robertson, BSc. Comments Can Barbituate help moderate Essential Tremor? January 25, at 1: Can Barbituate help moderate Essential Tremor? The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News-Medical. Post a new comment. Arsenic found in infant and toddler food. Rising health insurance costs frighten some early retirees. Prolonged use of PPIs linked with two-fold increased risk of stomach cancer, study finds. Brain function does not die immediately after the heart stops finds study. An alternative approach to augmenting the effect of antibiotics in chronic CF lung infections Dr Michael Graz and Dr Graham Dixon There are about 77, people known to have cystic fibrosis. Studying the nanomechanical properties of aging and cancerous cells using AFM Prof. Igor Sokolov Force microscopy is a technique which would probably be best described with the help of a small finger with an apex just a few atoms in size that can touch objects. Type 3c diabetes commonly mistaken for type 2 diabetes - study. Living with Ehlers-Danlos Syndrome. Researchers develop new drug screening method for rapid, accurate identification of fentanyl. Molecular method reveals brain circuitry essential for alertness. Research provides path to possible treatment for Fragile X Syndrome and other types of autism. UofL researchers help discover new autoimmune disease that causes kidney failure. Newsletters you may be interested in. Epilepsy Subscribe or Preview. Sleep Disorder Subscribe or Preview.

Barbiturates

Перевод 'barbiturates' на русский

Барбитураты

What are Barbiturates?

ДЕПРЕССАНТЫ | БАРБИТУРАТЫ

Перевод 'barbiturates' на русский

Barbiturates

Что такое Барбитураты

Barbiturate

ДЕПРЕССАНТЫ | БАРБИТУРАТЫ

Что такое Барбитураты

Barbiturates

Барбитураты

Перевод 'barbiturates' на русский

ДЕПРЕССАНТЫ | БАРБИТУРАТЫ

Барбитураты

ДЕПРЕССАНТЫ | БАРБИТУРАТЫ

Что такое Барбитураты

Перевод 'barbiturates' на русский

Barbiturate

Barbiturates

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