BPC -157

What is BPC-157?

BPC-157 refers to Body Protection Compound, a naturally occurring peptide found in human stomach juices. Composed of a sequence of 15 amino acids, the peptide can also be found in trace amounts in the gastric fluids of other mammals.

The peptide plays a fundamental role in preserving the lining of the GI tract. However, researchers are interested in its application in other areas of the body—particularly in regards to wound healing, neuroprotection, and muscle and tissue growth.

Much of the research on BPC-157 to date has been done in laboratory animals, but researchers are now using the findings to date to help direct further research into the ways BPC-157 may be beneficial for human subjects.

What Does BPC-157 Do?

BPC-157 was first isolated from body protection compound (BPC), which is found in the gastric juices and is part of the digestive process. It is composed of 15 amino acids, with the following chemical composition:

The role of BPC in the gastric juice is an important one. As a compound that can promote healing, it helps protect the gastrointestinal tissues from damage and can help prevent and heal stomach ulcers or other injuries to the intestinal lining.

It also promotes angiogenesis, or the formation of new blood vessels, allowing for increased oxygenation to the tissues.

Because of these properties, isolated BPC-157 is of great interest to researchers. The peptide shows potential in a number of applications outside of the GI tract, including in its promotion of healing, muscle growth and repair, and injury recovery.

Overview.

 Connects the brain and the digestive system: BPC-157 may play a role in the gut-brain axis, or the direct line of communication between the nervous system and the digestive system. Perhaps surprisingly, the two are deeply interconnected—with digestive health playing a significant role in neurological health and cognitive function

 Neuroprotection: BPC-157 has been shown to provide some neuroprotective effects in rats, helping to protect against harmful free radical damage or protect the brain and preserve brain function after exposure to harmful substances

 Improved memory: BPC-157 may help improve and preserve memory as a result of its neuroprotective effects.

 Mood regulation: Its neuroprotective effects may also help with mood regulation.

 Blood flow and angiogenesis: One of the most promising potential benefits of BPC-157 is its angiogenic effect, or its ability to promote the formation of new blood vessels, which may help improve vasculature and blood flow. This effect has been noted in rat studies

 Reduced physical discomfort: Some early preclinical research suggests that BPC-157 may have nociceptive (pain relieving) properties. This effect was actually noted in a small chart review in humans—one of the few uses of BPC-157 that has human evidence at this time

 Increased energy: Because it can activate NO pathways, BPC-157 may help provide an energy boost. NO activators are a common ingredient in pre-workout supplements

 Wound healing: The angiogenic properties of BPC-157 may also promote faster wound healing. It naturally occurs in the gastric juice and helps to prevent gastric ulcers, and researchers have found that it also helps promote faster healing of wounds in rats

 Liver protection: In laboratory animal studies, BPC-157 may be able to help protect the stomach, liver, and other tissues from NSAID medication overdoses. Researchers theorize it may offer similar protective benefits against alcohol and other toxins

 Muscle and tissue growth: In test-tube studies, BPC-157 stimulates growth hormone receptor expression—signalling the body to create new tendon tissue. It may also offer similar effects for bone, skin, and muscle

BPC-157 Dosage Calculator

In general, the most widely agreed upon daily dose of BPC-157 is about 250 mcg, delivered via intramuscular injection. A general rule of thumb that may be utilized by researchers is 2-4 mcg per kg of body weight.