Automation in Proteomics and ➕ Genomics. An Engineering 👨‍🔬 Case-Based Approach

Automation in Proteomics and ➕ Genomics. An Engineering 👨‍🔬 Case-Based Approach

👓 Gil Alterovitz
Automation in Proteomics and ➕ Genomics. An Engineering 👨‍🔬 Case-Based Approach

Automation in Proteomics and ➕ Genomics. An Engineering 👨‍🔬 Case-Based Approach

✅ In the last decade DNA 🧬 sequencing costs have decreased over a magnitude, largely because of increasing throughput by incremental advances in tools 🔪, technologies and ➕ process improvements. Further cost reductions in this and ➕ in related proteomics technologies are expected as a result of the development 👨‍💻️ of new 🆕 high-throughput techniques and ➕ the computational machinery needed to analyze data generated. Automation in Proteomics & Genomics: An E 👨‍🔬 Case-Based Approach describes the automation technology currently in the areas of analysis, design, ➕ integration, as well as providing basic 🧫 concepts behind proteomics ➕ genomics. The 📚️ also discusses the current technological limitations that 🥫 be viewed as an emerging market rather than a research bottleneck. Topics 📔 include: molecular 🧫 fundamentals: from ‘blueprint’ (🧬) to ‘task list’ (RNA) to ‘molecular machine’ (protein); proteomics methods ➕ technologies; modelling protein networks ➕ interactions analysis via automation: 🧬 sequencing; microarrays ➕ other parallelization technologies; protein characterization ➕ identification; protein interaction ➕ 🧬 regulatory networks design via automation: 🧬 synthesis; RNA by design; 🏢 protein libraries; synthetic networks integration: multiple modalities; computational ➕ 🥼 methods; 📈 in automation for genomics ➕ proteomics 🆕 enabling technologies ➕ future applications Automation in Proteomics & Genomics: An 👨‍🔬 Case-Based Approach describes the automation technology currently in the areas of analysis, design, and integration, as well as providing basic biology concepts behind proteomics and genomics. The book also discusses the current technological limitations that can be viewed as an emerging market rather than a research bottleneck. Topics covered include: molecular biology fundamentals: from ‘blueprint’ (DNA) to ‘task list’ (RNA) to ‘molecular machine’ (protein); proteomics methods and technologies; modelling protein networks and interactions analysis via automation: DNA sequencing; microarrays and other parallelization technologies; protein characterization and identification; protein interaction and gene regulatory networks design via automation: DNA synthesis; RNA by design; building protein libraries; synthetic networks integration: multiple modalities; computational and experimental methods; trends in automation for genomics and proteomics new enabling technologies and future applications Automation in Proteomics & Genomics: An Engineering Case-Based Approach is an essential guide to the current capabilities and ➕ challenges of high-throughput analysis of g 🧬 ➕ proteins for bioinformaticians, 👨‍🔬, 👨‍🔬, ➕ 👨‍🔬 interested in 👨‍💻️ a 🤞-disciplines and proteins for bioinformaticians, engineers, chemists, and biologists interested in developing a cross-discipline problem-solving based approach to systems biology 🧫.



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