Atopobium Vaginae

Atopobium Vaginae




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Atopobium Vaginae


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Archives of Gynecology and Obstetrics
Arch Gynecol Obstet. 2019; 300(1): 1–6.
Published online 2019 Apr 5. doi: 10.1007/s00404-019-05142-8
1 German Center for Infections in Obstetrics and Gynaecology, Wuppertal, Germany
2 Labfit-HPRD: Health Products Research and Development, Lda, Covilhã, Portugal
3 CICS-UBI: Health Sciences Research Centre, University of Beira Interior, Covilhã, Portugal
4 Scientific and Medical Department, Medinova AG, Zurich, Switzerland
Werner Mendling, Email: ed.enilno-t@gnildnem.w .
Received 2019 Jan 23; Accepted 2019 Mar 26.
Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Keywords: Bacterial vaginosis, Bacterial biofilm, Atopobium vaginae , Metronidazole, Clindamycin, Dequalinium chloride, Microbial resistance
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1. Kenyon C, Colebunders R, Crucitti T (2013) The global epidemiology of bacterial vaginosis: a systematic review. Am J Obstet Gynecol [ PubMed ] [ Ref list ]
2. Srinivasan S, Fredricks DN. The human vaginal bacterial biota and bacterial vaginosis. Interdiscip Perspect Infect Dis. 2008; 2008 :750479. doi: 10.1155/2008/750479. [ PMC free article ] [ PubMed ] [ CrossRef ] [ Google Scholar ] [ Ref list ]
3. Donders G. Diagnosis and management of bacterial vaginosis and other types of abnormal vaginal bacterial flora: a review. Obstet Gynecol Surv. 2010; 65 :462–473. doi: 10.1097/OGX.0b013e3181e09621. [ PubMed ] [ CrossRef ] [ Google Scholar ] [ Ref list ]
4. Nasioudis D, Linhares IM, Ledger WJ, Witkin SS. Bacterial vaginosis: a critical analysis of current knowledge. BJOG. 2017; 124 :61–69. doi: 10.1111/1471-0528.14209. [ PubMed ] [ CrossRef ] [ Google Scholar ] [ Ref list ]
5. Witkin S (2014) The vaginal microbiome, vaginal anti-microbial defence mechanisms and the clinical challenge of reducing infection-related preterm birth. BJOG [ PubMed ] [ Ref list ]
6. Menard JP, Mazouni C, Salem-Cherif I, Fenollar F, Raoult D, Boubli L, Gamerre M, Bretelle F. High vaginal concentrations of Atopobium vaginae and Gardnerella vaginalis in women undergoing preterm labor. Obstet Gynecol. 2010; 115 :134–140. doi: 10.1097/AOG.0b013e3181c391d7. [ PubMed ] [ CrossRef ] [ Google Scholar ] [ Ref list ]
7. Srinivasan S, Hoffman NG, Morgan MT, Matsen FA, Fiedler TL, Hall RW, Ross FJ, McCoy CO, Bumgarner R, Marrazzo JM, Fredricks DN. Bacterial communities in women with bacterial vaginosis: high resolution phylogenetic analyses reveal relationships of microbiota to clinical criteria. PLoS ONE. 2012; 7 :e37818. doi: 10.1371/journal.pone.0037818. [ PMC free article ] [ PubMed ] [ CrossRef ] [ Google Scholar ] [ Ref list ]
8. Cox C, Watt AP, McKenna JP, Coyle PV. Mycoplasma hominis and Gardnerella vaginalis display a significant synergistic relationship in bacterial vaginosis. Eur J Clin Microbiol Infect Dis. 2016; 35 :481–487. doi: 10.10
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