Anti-Cancer Effects Of Xao Tam Phan Paramignya Trimera Methanol Root Extract On Human Cancer Of The Breast
Xao tam phan (Paramignya trimera (Oliv.) Guillaum) can be a Vietnamese traditionally medicinal plant utilized in treating numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. These studies aimed to analyze the effects of five various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The outcome indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the greatest antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (except for total flavonoids) and antioxidant capacity, when compared with conventional and ultrasound-assisted extractions. These data demonstrate that using methanol and microwave-assisted extraction are suggested for extraction of biologically active phytochemicals from P. trimera root for application from the nutraceutical and/or pharmaceutical industries.
Drying methods, solvents and extraction methods greatly affect the phytochemical compounds and biological activity from plant materials. The aims of this study could determine the effects of various drying methods, various solvents and extraction methods around the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root from Vietnam. The outcomes established that microwave drying was a powerful method in removing water with regards to shortest drying time, lowest energy consumption and greatest retention of phytochemical compounds and antioxidant capacity from your P. trimera root while methanol and microwave-assisted extraction were the very best solvent and way for greatest extraction with the phytochemical compounds and antioxidant capacity in the P. trimera root. The findings because of this study allow retaining the very best amounts of phytochemical compounds and antioxidant capacity through the P. trimera root for potential application within the nutraceutical industry.
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