Anti-Cancer Benefit Of Xao Tam Phan Paramignya Trimera Methanol Root Extract On Human Cancer Of The Breast

Anti-Cancer Benefit Of Xao Tam Phan Paramignya Trimera Methanol Root Extract On Human Cancer Of The Breast


Xao tam phan (Paramignya trimera (Oliv.) Guillaum) is often a Vietnamese traditionally medicinal plant found in the treatment of numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. These studies aimed to analyze the end results of five various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The outcome indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the maximum antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (apart from total flavonoids) and antioxidant capacity, in comparison to conventional and ultrasound-assisted extractions. These data reveal that using methanol and microwave-assisted extraction are recommended for extraction of biologically active phytochemicals from P. trimera root for application from the nutraceutical and/or pharmaceutical industries.

Drying methods, solvents and extraction methods greatly impact the phytochemical compounds and biological activity from plant materials. The aims of this study would determine the end results of different drying methods, various solvents and extraction methods on the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root extracted from Vietnam. The final results showed that microwave drying was an efficient method in elimination of water regarding shortest drying time, lowest energy consumption and greatest retention of phytochemical compounds and antioxidant capacity from your P. trimera root while methanol and microwave-assisted extraction were the very best solvent and way of greatest extraction from the phytochemical compounds and antioxidant capacity through the P. trimera root. The findings using this study allow retaining the very best amounts of phytochemical compounds and antioxidant capacity through the P. trimera root for potential application inside the nutraceutical industry.

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