Alcohol risks

https://www.nature.com/articles/1601486.pdf?origin=ppub - It is important to highlight that moderate consumption seems to have a better impact on the immune system than excessive or absence of consumption (2002)

https://www.nature.com/articles/hr200790.pdf?origin=ppub - increased hypertension risk(2007)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307043/ - alcohol use is associated with tremendous costs to the drinker, those around him or her, and society as a whole. These costs result from the increased health risks (both physical and mental) associated with alcohol consumption as well as from the social harms caused by alcohol. (2011)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179594/ - Most studies have found a J-shaped relationship between alcohol consumption and health benefits. Moderate daily alcohol use (1 drink/day in women and 1–2 drinks/day in men) has been shown to provide the most benefit. (2012)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590617/ - The most common and identifiable alcohol-associated health problems include liver cirrhosis, pancreatitis, cardiomyopathies, neuropathies, and dementia. However, the lung also is adversely affected by alcohol abuse, a fact often overlooked by clinicians and the public(2015)

https://www.thelancet.com/article/S0140-6736(18)31310-2/fulltext - tuberculosis , road injuries, self-harm, cancer. The level of alcohol consumption that minimised harm across health outcomes was zero standard drinks per week.(2016)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981808/ - Regular alcohol intake has both risks and benefits. In analyses using repeated assessments of alcohol over time and deaths from all causes, women with low to moderate intake and regular frequency (> 3 days/week) had the lowest risk of mortality compared with abstainers and women who consumed substantially more than 1 drink per day. (2016)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513687/ - cardiovascular system (2017)

https://www.nature.com/articles/bdjteam201825.pdf?origin=ppub - problems with teeth: Periodontal disease, oral malodour, Patients with chronic alcoholism have significantly more dental wear, cancer(2018)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633071/ - highlight the profound and extensive implications of alcohol-related harms for individuals and larger populations, casting doubt on previous hypotheses regarding alcohol potentially having favorable effects on certain conditions and explicitly indicating that no level of alcohol intake is safe.(2019)

https://www.nature.com/articles/s41598-019-52754-w - The results suggest that higher risk of harm from alcohol use was associated with two of the eight NCD risk factors among women (higher blood pressure and higher triglyceride level) and five of the eight NCD risk factors among men (smoking, physical inactivity, higher blood pressure, higher blood glucose and higher triglyceride level). NCD = non-communicable diseases(2019)

https://www.nature.com/articles/s41598-019-44302-3 - chronic alcohol drinking, regardless of dose alters resting transcriptomes of PBMC, with the largest impact seen in innate immune cells.(2019)

https://www.nature.com/articles/s41416-020-01101-2 - higher risk for cancer in higher parts of digestive systems, higher risk of breast cancer for woman (2020)

https://www.nature.com/articles/s41598-020-70304-7 - decreased risk of major adverse cardiovascular events (MACE) among <=1 glass per day. Increased mortality from external causes in case of >=2 glass per day(2020)

https://www.nature.com/articles/s41598-020-62227-0 - For men, drinking more than 21 units (approximately 168 grams) of alcohol per week, was associated with waking several times a night(2020)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020057/ - Besides new evidence associating low and moderate alcohol consumption with decreased risk of cardiovascular disease, several questions remain unanswered related to the concrete amount of safe consumption, the type of alcoholic beverage, and the age-, sex-, and genetic/ethnical-specific differences in alcohol consumption. (2020)

https://www.nature.com/articles/s41598-020-70910-5 - decreased brain volume in early middle-agers(2020)

https://www.nature.com/articles/s41598-021-84804-7 - GreyMatter reduction in AUD could disrupt network communication responsible for the neurocognitive impairments associated with high chronic alcohol consumption.(2021)

 https://www.nature.com/articles/s41598-021-84181-1 - Alcohol consumption was significantly and positively associated with an increased risk of cancer mortality in a dose-dependent manner, beginning with light drinkers.(2021)

https://www.nature.com/articles/s41598-021-81777-5 - more alcohol consumption was associated with lesser decline in kidney function over 12 years among the general population in Korea, especially men.(2021)