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It is derivative of the substituted phenethylamine 2C-I and is the most well-known member of the NB family. Street names and media nicknames for this drug are: Although 25I-NBOMe was discovered in , it did not emerge as a common recreational drug until , when it was first sold by vendors specialising in the supply of research chemicals. Due to its potency and much lower cost than so-called classical or traditional psychedelics, 25I-NBOMe blotters are sometimes misrepresented as, or mistaken for LSD blotters. However, this route of administration is very dangerous, unless using precise liquid measurement, due to the difficulties of measuring and handling substances active in the microgram range. Case reports of seven British males who presented to an emergency room following analytically confirmed 25I-NBOMe intoxication suggest the following potential adverse effects: Recreational use of 25I-NBOMe carries significant risk of both pharmacological and behavioral toxicity. The LD 50 has not yet been determined. Reports of deaths and significant injuries have been attributed to the use of 25I-NBOMe, prompting some governments to control its possession, production, and sale. The website Erowid states that 25I-NBOMe is extremely potent and should not be snorted as this method of administration 'appears to have led to several deaths in the past year. He was reported to have consumed caffeinated alcoholic beverages for 'several hours' beforehand. It is unclear what other drugs he may have consumed, as autopsies generally do not test for the presence of research chemicals. The drug is the suspected cause of death in another Scottsdale, Arizona, incident in April He reportedly jumped off a balcony thinking he could fly. At least one of the teenagers suffered a cardiac arrest , according to reports, along with extreme internal bleeding. While in-vitro studies showed that N -benzyl derivatives of 2C-I were significantly increased in potency compared to 2C-I, the N -benzyl derivatives of the related compound DOI were inactive. This substitution significantly increases the potency of the molecule. Analogues and derivatives of 2C-I:. It can be done stepwise by first making the imine and then reducing the formed imine with sodium borohydride , or by direct reaction with sodium triacetoxyborohydride. The Australian federal government has no specific legislation concerning any of the N-benzyl phenethylamines. Russia was the first country to pass specific regulations on the NBOMe series. In , Romania banned all psychoactive substances. From Wikipedia, the free encyclopedia. Anlage I Authorized scientific use only UK: Class A \\\\\\\\\\\\\\\\\[1\\\\\\\\\\\\\\\\\] US: Counterculture Entheogen Smart shop Trip sitter Psychedelic microdosing. Bad trip Ecology Ego death Serotonergic psychedelic Therapy. Drug policy of the Netherlands Drug liberalization Legality of cannabis Legal status of psilocybin mushrooms Legal status of Salvia divinorum. Analogues and derivatives of 2C-I: Entwicklung eines neuen Struktur-Wirkungskonzepts' in German. Journal of Nuclear Medicine. Dangerous synthetic drug making its way across the country. Archived October 31, , at the Wayback Machine. New York Daily News. Retrieved 7 May Patterns of use, characteristics of users and self-reported effects in a large international sample'. Polkis; Alphone Polkis March Journal of Analytical Toxicology. Advisory Council on the Misuse of Drugs. Journal of Pharmacology and Experimental Therapeutics. Journal of Computer-Aided Molecular Design. China Food and Drug Administration. Retrieved 1 October Official Journal of the European Union. Archived from the original on May 13, Retrieved May 15, Diphenidine Ephenidine Fluorolintane Methoxphenidine. Dextrallorphan Dextromethorphan Dextrorphan Racemethorphan Racemorphan. Apomorphine Aporphine Bromocriptine Cabergoline Lisuride Memantine Nuciferine Pergolide Phenethylamine Piribedil Pramipexole Ropinirole Rotigotine Salvinorin A Also indirect D 2 agonists, such as dopamine reuptake inhibitors cocaine , methylphenidate , releasing agents amphetamine , methamphetamine , and precursors levodopa. Glaucine Isoaminile Noscapine Pukateine. AR-A Beta blockers e. Agomelatine Atypical antipsychotics e. Adatanserin Agomelatine Atypical antipsychotics e. Alosetron Arazasetron AS Atypical antipsychotics e. ABT Atypical antipsychotics e. Retrieved from ' https: Views Read Edit View history. This page was last edited on 17 September , at By using this site, you agree to the Terms of Use and Privacy Policy. Buccal sublabial , sublingual , insufflated , inhalation , intravenous , intramuscular , rectal. Part of a series on. Law Drug policy of the Netherlands Drug liberalization Legality of cannabis Legal status of psilocybin mushrooms Legal status of Salvia divinorum. Pharmacy and Pharmacology portal.

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