7 Simple Tips For Moving Your Tumor Treating Fields Mesothelioma
Tumor Treating Fields Mesothelioma
Tumor treating fields mesothelioma, a brand new type of therapy, uses alternating electric field to slow the growth of cancer. It is utilized in conjunction with chemotherapy to treat pleural cancer.
The FDA approved TTFields concomitant with pemetrexed and cisplatin in 2019 after the successful STELLAR trial. Patients can ask their specialist for this treatment.
Disrupting Cell Division
TTFields use different electrical fields to disrupt cancer cell proteins and prevent their cells from growing. This will stop mesothelioma expanding or growing in other organs. The TTFields also help to increase the production of proteins that can destroy cancerous cells and help the immune system fight mesothelioma tumors.
During treatment patients wear a small device with insulated pads that are bonded to the skin. The device delivers an electrical current of low intensity and the patient is able to decide how much treatment they receive. A mesothelioma therapy session lasts approximately 30 minutes. Patients can receive the TTFields Treatment several times per day.
A TTFields study that was published in 2021 showed that the intensity of the electrical field of 100 to 300 Kilohertz could stop the division of cancer cells and cause them to die. The study covered a variety of cancerous cells and found that electrical fields killed all of them regardless of their cellular structure.
The study's author suggested combining TTFields and chemotherapy for mesothelioma. Novocure's TTFields product, NovoTTF-100L, was approved by the FDA in 2019 to treat pleural mesothelioma that is not resectable. It is now available from mesothelioma specialists from accredited medical centers in the U.S. including the West Cancer Center, Memphis. The NovoTTF-100L device, which is now known as Optune Lua, has been used to treat mesothelioma combination with chemotherapy based on platinum. Mesothelioma victims have reported an extended survival time when the TTFields treatment has been combined with chemotherapy.
Another study, which was published in "Lung Cancer", reported that TTFields therapy is highly effective in conjunction with chemotherapy. Researchers found that the combination of chemotherapy and TTFields significantly reduced the number of mesothelioma cancerous cells in animal models. The study also revealed that combing these treatments boosted the production of proteins that kill mesothelioma tumor cells and reduce the amount or cancerous DNA that is found in your body.
Despite being an emerging treatment, a lot of mesothelioma specialists don't offer TTFields for pleural mesothelioma. new mesothelioma treatment may still have access to this treatment through clinical trials or at Novocure-certified mesothelioma clinics.
Stalling Tumor Growth
Mesothelioma develops when mesothelial cells mutate and outlive their normal lifespan, leading to an overabundance of cancerous cells that grow and spread throughout the body. Tumor treating fields stop mesothelioma tumors from spreading and growing by blocking mesothelial cells from duplicated.
The TTFields device is worn on the chest similar to an armband and generates a series of electrical fields that alter proteins that kill cancer cells and slow the growth of tumors. The device comes with insulated pads which adhere to the skin. Patients or health care professionals can apply the pads at home.
Doctors suggest mixing TTFields with chemotherapy to achieve the best results. The combination boosts production of proteins that kill cancer cells and reduces cancer cells' ability to repair DNA damage from chemotherapy drugs. This allows the chemotherapies to work even harder, and increases the survival rate of mesothelioma patients.
In the recent STELLAR trial, a combination of TTFields therapy and chemotherapy significantly improved survival for mesothelioma sufferers. In 2019, the FDA approved the NovoTTF 100L System, now marketed under Optune Lua for use with pemetrexed, cisplatin, or carboplatin, as a primary treatment of malignant pleural melanoma that is not surgically resectable.
Researchers have discovered that the TTFields treatment can fight mesothelioma by stopping cell division. The treatment TTFields causes cancer cells to break down through a process known as mitosis. The cells get trapped in surrounding tissues, which inhibits the growth of new tissue. Mitosis blocks mesothelioma cancer cells from healing damaged genetic material and makes them more susceptible to radiation treatment.
The TTFields treatment may also reduce tumor blood flow by reducing vascular endothelial growth factor, or VEGF, and by increasing hypoxia-inducible factor-1 beta, or HIF-1a, which is linked with cancer cell angiogenesis.
Talk to your doctor in the event that you've been diagnosed with mesothelioma. Novocure and a number of mesothelioma specialists are conducting clinical trials to evaluate the efficacy of TTFields. Contact an Novocure certified specialist at one of the more than 1,300 U.S. Treatment Centers to find out more about the mesothelioma treatment options with TTFields.
Killing Tumor Cells
Tumor treating fields for treating tumors (TTFields) disrupt cell division by sending electrical waves through the body to destroy tumor cells. They are low-intensity and medium frequency electric fields that alternately target cancerous cells without harming healthy ones. These electric fields also reduce DNA repair and increase cell defenses, making it harder for cancerous cells to survive. TTF is a non-invasive treatment and has few side effects other than mild skin irritation.
Scientists believe TTFields work by interrupting mitosis, a process by which the cell divides into two identical cells. Normal cells have controls to restrict mitosis. However cancerous tumors of malignancy can break these limitations and multiply at a rapid rate. TTFields interferes with this process by blocking signals that control the process of mitosis in mesothelioma cancer cells. In the STELLAR trial, TTFields in combination with chemotherapy improved survival rates for mesothelioma. Mesothelioma survivors who received TTFields along with maintenance cycles of chemotherapy survived six months longer on average than those who just received chemotherapy.
In a different study, it was discovered that TTFields could boost the effectiveness of certain chemotherapy drugs called platinum-based treatments. These platinum-based therapies kill mesothelioma by targeting mitochondria. This is where the energy of cancerous cells comes from. When TTFields is combined with these chemotherapies the combination can result in higher levels of DNA damage as well as faster cancer cell death.
TTFields may also boost the effects of radiation therapy in certain cases. Researchers have discovered that combining TTFields with radiation therapy may create a "synergistic effect." This means that the combined treatments increase the sensitivity of mesothelioma cells to radiation.
Currently, TTFields are available at certain mesothelioma centres. A mesothelioma expert will determine if you're suitable for this treatment. If you're eligible an attorney for mesothelioma can help you access treatment that includes TTFields with chemotherapy. If you are an active military veteran mesothelioma lawyer could help you access treatment that is covered under your VA health benefits.
Side Effects
The TT fields therapy disrupts the cancer cells by creating a field of electricity that blocks their ability to divide. This can slow down the growth of tumors and prevent it from spreading to other parts of the body. The TT fields device is non-invasive, which means it does not damage the surrounding tissue or cause pain. This is in contrast to conventional chemotherapy, which requires intravenous injections or radiation, both of which can cause severe side effects.
In a study in which patients were who received a combination of TT fields and temozolomide saw survival improvements comparable to people who were only treated with chemo. Doctors attributed this increased survival to TT fields, which increase the effectiveness of chemo while reducing side adverse effects.
Mesothelioma cancer cells may mutate and multiply uncontrollably, causing the tumor to spread into your organs. Mesothelioma treatments like TT fields stop mesothelioma cells from reproducing and limiting the body's normal functions through stopping the division of cells.
In a mesothelioma study, mesothelioma patients who received TT fields in conjunction with their chemo had an average survival of 18.2 months. Those who received TT fields but not chemotherapy had a rate of 12.1.
Tumor-treating fields are applied to the pleura, or the thin lining that surrounds your lungs, on your chest or abdominal wall. The device is small enough to be worn for up to 18 hours per day, including sleep. Patients can live their lives and continue working while receiving treatment.
TT fields can be combined with conventional chemotherapy or immunotherapy as well as other mesothelioma treatments. Patients with mesothelioma who are interested in TT should discuss the option with their physician. They can provide eligibility requirements and benefits predicted for each patient's particular case.