High Intensity Sweeteners: Science and Controversy Date: September 22-24, 2015 Plenary lecture - The Ecology of Sweetness – Gary Beauchamp, Past Director, Monell Chemical Senses Center Session 1 - The regulation and Use of high intensity sweeteners (Chair – Kendall Wallace, PhD, Professor and Associate Dean for Faculty Affairs, University of Minnesota Medical School, Duluth) The regulatory process for sweetener approval – Ashley Roberts, PhD, Senior Vice President, Intertek Scientific & Regulatory Consultancy Trends in high intensity sweetener use – Allison Meni, PhD, Visiting Assistant Professor, George Washington University Session 2 - Sweet taste mechanisms and perception (Chair – Bruce Hamaker, PhD, Professor, Purdue University) Molecular mechanism of sweet sensation - Grant Dubois, PhD, Sweetness Technologies, LLC Sweetness and appetite – Peter Rogers, PhD, Professor, University of Bristol Sweetness and learning – Ivan Eid Tavares De Araujo, PhD Associate Professor, Yale School of Medicine
Lunch and Poster Session Session 3 - High intensity sweetener use and gut function I – digestion, endocrine responses and glucose absorption (Chair - Robert Considine, PhD, Professor, Indiana University School of Medicine) Chris Beglinger, PhD, Professor, University Hospital of Basel John McLaughlin, PhD, Professor, University of Manchester Session 4 - High intensity sweetener use and gut function II – microbiota (Chair – Mario Ferruzzi, PhD, Professor, Purdue University) Jane Shearer, PhD, Associate Professor, University of Calgary Soraya Shirazi-Beechey, PhD, Professor, University of Liverpool Session 5 - HIS use and the brain (Chair - David Kareken, PhD, Associate Professor, Indiana University School of Medicine) Nicole Avena, PhD, Assistant Professor, Mount Sinai School of Medicine John Glendinning, PhD, Professor, Barnard College, Columbia University Session 6 - HIS use and energy balance (Chair - Richard Mattes, PhD, RD, Distinguished Professor, Purdue University)
Sharon Fowler, MPH, Adjunct Assistant Professor, UT Health Science Center at San Antonio John Peters, PhD, Professor, University of Colorado Concluding Panel Discussion – Where are the key gaps of knowledge and most important next steps to address them? (Chair - Nana Gletsu-Miller, PhD, Assistant Professor, Purdue University) The Ingestive Behavior Research Center at Purdue University is unique in providing an interdisciplinary research and training environment that promotes excellence in the analysis of ingestive behavior and its disorders. Individual and population-based health practices will be optimized by advancing understanding of the controls of ingestive behavior. Current Events7IBRC Journal Club March 7 @ 11:00 AM - 12:00 PM STON B24IBRC Journal Club April 4 @ 11:00 AM - 12:00 PM STON B22IBRC Journal Club May 2 @ 11:00 AM - 12:00 PM STON B2 Dr. Richard Mattes, Ph.D., Director Dr. Wayne Campbell, Ph.D. Dr. Mario Ferruzzi, Ph.D. Dr. Kimberly Kinzig, Ph.D.
Dr. Blake L. Jones, Ph.D. Dr. Bryce Carlson, Ph.D. Cresta CatesAdministrative AssistantPurdue UniversityStone Hall, Room 220700 W. State Street West Lafayette, IN 47907-2059 catesc@purdue.edu(765) 494-5735 phone(765) 494-0674 faxThe Biology of Aging “Advances in Therapeutic Approaches to Extend Healthspan” The Scripps Research Institute, Jupiter Florida Welcoming Comments - Dr. Paul Robbins, TSRI 7:05 – 7:45 pm S. Jay Olshansky, University of Illinois at Chicago 7:45 – 8:25 pm Felipe Sierra, Director, National Institute on Aging 8:25 - 9:05 pm Steven Austad, University of Alabama - Birmingham Session 1: Drug Screening/Testing (Chair: James Kirkland) Gordon Lithgow - Buck Institute Michael Petracheck - The Scripps Research Institute Richard Miller - University of Michigan Rafael de Cabo - National Institute on Aging Laura Niedernhofer - The Scripps Research Institute Randy Strong - UT San Antonio
Session 2: Anti-Geronic Factors (Chair: Judy Campisi) Amy Wagers - Harvard University Brian Kennedy - Buck Institute Andrzej Bartke - Southern Illinois Session 3: Senotherapeutics (Chair: David Sinclair) James Kirkland - Mayo Clinic Judy Campisi - Buck Institute Andrei Gudkov - Roswell Park Cancer Institute/Everon Biosciences Thomas von Zglinicki - Newcastle University Paul Robbins - The Scripps Research Institute Poster Session/Reception - Scripps Cafe Dinner at Scripps Florida - Back Patio Session 4: Genetic Identification of Targets for Drug Development (Chair: Jan Vijg) Yousin Suh - Albert Einstein Alan Shuldiner - Regeneron Jan Hoeijmakers - Erasmus Nicholas Schork - JCVI Session 5: Molecular Targets for Drug Development (Chair: Steve Austad) David Sabitini - MIT Ana Maria Cuervo - Albert Einstein David Sinclair - Harvard University Anne Brunet - Stanford University
Roundtable Discussion with NIA Scientific Review Officers - Graduate Students, Post-doc's and Junior Faculty Session 6: Stem Cell and Stem Cell Factors (Chair: Amy Wagers) Heinrich Jasper - Buck Institute Johnny Huard - UT Houston Georgina Ellison - Kings College Gala Dinner - Loggerhead Marinelife Center Session 7: Clinical Trials on Aging (Chair: Arlan Richardson) Joan Mannick– Novartis Institutes for BioMedical Research Nir Barzilai– Albert Einstein Tony Wyss-Coray– Stanford University Jill Crandell– Albert Einstein Peter Rabinovitch– University of Washington Session 8: Panel Discussion (Moderator: Paul Robbins) Nir Barzilai - Albert Einstein James Kirkland - Mayo Felipe Sierra - NIA Kevin Lee - Glenn Foundation James Goldenberg - Medical Specialists of the Palm Beaches Will Maier - MAPI CGSB Auditorium, 12 Waverly Place The NY/BIG conference is a meeting of Bacillus researchers located in the Northeastern United States.
Chair - Patrick Eichenberger (NYU) Adam Driks (Loyola University Chicago): “BclA is present on the surface of spores of diverse species” Kerry Boyle (Xavier lab, Memorial Sloan-Kettering Cancer Center): “The metabolomic basis of social behavior" Jeanie Dubnau (Dubnau lab, PHRI): "A tale of two models: the roles of the "Y-complex" in B. subtilis development" Michael DeLay (Sahin lab, Columbia): “Nano-confinement effects on spore water transport” Elizabeth Libby (Dworkin lab, Columbia): “Noise in signaling systems drives phenotypic variability in antibiotic tolerance” Jon McGinn (Marraffini lab, Rockefeller): "Spacer acquisition during type II CRISPR immunity” Chair - Jonathan Dworkin (Columbia University) KEYNOTE: Harris Wang (Columbia) ”Synthetic and systems biology approaches to study and manipulate horizontal gene flow” Liz Mearls (Mt Holyoke, Camp lab): "Investigations of the metabolic status of the developing B. subtilis spore"
Cordelia Weiss (Winkler lab, University of Maryland): “B. subtilis subpopulations exhibit significant differences in levels of cyclic di-GMP” Mario Arrieta-Ortiz (Bonneau and Eichenberger labs, NYU): “Inferring the small non-coding RNA regulatory network of B. subtilis” Christine Diethmaier (Dubnau lab, PHRI): "A swim-win situation: how flagellar rotation influences K-state development in B. subtilis Lisa Kahl (Dietrich lab, Columbia): “Light- or temperature-controlled redox cycling in Pseudomonas aeruginosa biofilms” Chair - Adam Driks (Loyola University Chicago) Monika Buczek (Janakiraman lab, CCNY): “Proteolytic regulation of FtsZ-ring assembly in E. coli cytokinesis” Lei Rao (Setlow lab, UConn): "Revisiting old evidence supporting the expanded cortex model for spore wet heat resistance” Jonathan Karr (Mount Sinai): “Toward a community whole-cell model of B. subtilis” Kelly Flanagan (Camp lab, Mt Holyoke): “A role for membrane protein SpoIIQ in the specific gene regulation of an anti-σG factor during B. subtilis sporulation"
Jesse Hauver (Darst lab, Rockefeller): "Crystal structure of E. coli RNA polymerase holoenzyme with the lariat-peptide inhibitor microcin J25" and Nathaniel Braffman (Darst lab, Rockefeller): "Structure and function of the E. coli RNA polymerase lariat-peptide inhibitor capistruin" Jonathan Goodson (Winkler lab, University of Maryland): “A broadly conserved antiterminator protein controls a regulon of Bacillus amyloliquefaciens antibiotic gene clusters” Wine & Cheese Reception From Penn StationACE From NJFrom Elsewhere Oren's Daily Roast (Waverly Pl. & Greene St.) Waverly Area (Wraps, Crepe) Sit Down Dining Areas (Thai, Mexican, Asian, Italian) St. Marks Pl. (Mexican, Burgers) W. Houston St. (Italian, American) More Lunch Options (Google Maps) NY/BIG would like to thank the following groups and organizations for their support of the meeting: New York University, the Department of Biology at NYU, the Center for Genomics and Systems Biology at NYU, Columbia University, and the Department of Microbiology and Immunology at Columbia University.