J Int Med Res. 2001 Jul-Aug;29(4):381-4.Hattori M1, Morita N, Tsujino Y, Yamamoto M, Tanizawa T.Author information1Department of Pediatrics, Hyogo College of Medicine, Nishinomiya, Japan. hat-ped@hyo-med.ac.jpAbstractWe report a case of secondary osteoporosis treated with a combination of vitamins D3 and K2, administered orally. A 13-year-old male, diagnosed with highly differentiated acute myelogenous leukaemia, received an allogeneic bone-marrow transplantation. Chronic graft-versus-host disease persisted, thereafter, in the form of severe diarrhoea, rash and allergic conjunctivitis. Since the patient was then at risk from osteoporosis secondary to calcium malabsorption caused by the diarrhoea, dual-energy X-ray absorptiometry and ultrasound analysis were used to measure bone mineral density and bone stiffness, respectively. Both measurements were markedly lower than the average values from patients of matched age, gender and physical characteristics. The osteoporosis did not respond to active vitamin D3 0.1 microg/kg once daily, but when this therapy was combined with vitamin K2 15 mg once daily, an increase in bone mineral density and bone stiffness was observed.
In conclusion, vitamin D3 and K2 combination therapy merits further evaluation for the treatment of various types of secondary osteoporosis, including steroid-induced osteoporosis.PMID: 11675913 DOI: 10.1177/147323000102900416 [Indexed for MEDLINE] Publication typeCase ReportsMeSH termsAdolescentBone Density/drug effectsBone Marrow Transplantation/adverse effects*Cholecalciferol/therapeutic use*Graft vs Host Disease/complications*HumansLeukemia, Myeloid, Acute/therapyMaleOsteoporosis/drug therapy*Osteoporosis/etiology*Vitamin K 3/therapeutic use*SubstancesCholecalciferolVitamin K 3Full Text SourcesAtypon - PDFMedicalTransplantation - Genetic AllianceOsteoporosis - Genetic AllianceBone Marrow Transplantation - MedlinePlus Health InformationOsteoporosis - MedlinePlus Health InformationMiscellaneousCHOLECALCIFEROL - Hazardous Substances Data BankMENADIONE - Hazardous Substances Data Bank Conditions & Diseases A-ZADD / ADHDALS / Lou Gehrig's DiseaseAlzheimer's DiseaseCancerH. PyloriMigraine HeadachesMuscle Spasms / CrampsOsteoporosisProstatitis
Chocolate & Cocoa Benefits? Sterols, Sterolins & Beta-Sitosterol Muscle Spasms & Cramps DRI / RDA B-Vitamins Spiritual Health & Healing Osteoporosis / Bone Loss: Guidelines, Nutritional Causes, Treatment Remedies & Prevention Calcium + Vitamin DOsteopenia Common Drugs used to treat Osteoporosis include: • Fosamax, Fosavance, Actonel, Didronel / Didrocal World Health Organization standards for the diagnosis of Osteoporosis: Nutritional Treatments and Remedies for Osteoporosis: usually taken in the form of Silica (e.g from horsetail), is a natural trace mineral remedy that helps in the although a normal (RDA / DRI) intake of Vitamin A is required for Vitamin D to function properly. RDA / RDI for Vitamin D excessive supplemental intake of Vitamin D is capable of causing storage of calcium (calcification, spurs), resulting in bio-unavailability of calcium (see bottom of page). Sugar & Glycemic Index
See details and reasons why not High Calcium-related Osteoporosis may develop as a result of: • low stomach acid, H. Pylori infection, or long-term use of acid-lowering drugs, Increasing stomach acid levels DRI / RDA for Calcium & Magnesium + Vitamin A, Vitamin D, Vitamin K. This site uses cookies from advertisers (e.g. Google) to deliver its services, to personalize ads, and to analyze traffic. Continued use of this site constitutes acceptance of cookies in accordance with the EU Cookie Policy.Dr. Cannell on the treatment of osteoporosis, its complications and silicon As we age, many of us will develop osteoporosis. Compression fractures of the vertebra are a common painful complication of osteoporosis. Recently, a procedure called “vertebral augmentation” has been developed to treat compression fractures. Vertebral augmentation procedures are minimally invasive surgeries. Typically, the patient goes home the same day as the procedure, or in some cases after an overnight hospital stay.
The procedure involves injecting bone cement into the inside of the fractured vertebra in order to create an “internal cast” inside the bone, stabilizing the fracture and reducing the patient’s pain. Recently, researchers in Taiwan studied 79,000 patients who experienced at least one vertebral augmentation to determine the risk factors associated with having a repeat procedure. Eleven percent of these patients had to repeat the procedure over the six years they were followed. Liang CL, Wang HK, Syu FK, Wang KW, Lu K, Liliang PC. Repeated vertebral augmentation for new vertebral compression fractures of postvertebral augmentation patients: a nationwide cohort study. They found patients on vitamin D and calcium (unspecified dose) were almost 3 times less likely to need a repeat procedure. When I read this study, I wondered what the need for these procedures would have been if these elderly patients were required to take a good bone formula to combat their osteoporosis.
The one I recommend is Bone Restore with Vitamin K2 from Life Extension Foundation. While you need to take 5,000 IU/day of vitamin D with Bone Restore, this product has the other minerals that bone requires to help osteoporosis, such as magnesium, zinc, silicon, boron and vitamin K2. Bone needs more than vitamin D to be healthy. Silicon is especially important for treating osteoporosis and a recent review reinforced this. Rodella LF, Bonazza V, Labanca M, Lonati C, Rezzani R. A review of the effects of dietary silicon intake on bone homeostasis and regeneration. J Nutr Health Aging. Even a RCT showed favorable effects of silicon on bone. Spector TD, Calomme MR, Anderson SH, Clement G, Bevan L, Demeester N, Swaminathan R, Jugdaohsingh R, Berghe DA, Powell JJ. Choline-stabilized orthosilicic acid supplementation as an adjunct to calcium/vitamin D3 stimulates markers of bone formation in osteopenic females: a randomized, placebo-controlled trial. Did you know there is even a randomized controlled trial showing silicon supplementation helps skin appearance and brittleness of fingernails in women with sun-damaged skin?
Barel A, Calomme M, Timchenko A, De Paepe K, Demeester N, Rogiers V, Clarys P, Vanden Berghe D. Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin. Arch Dermatol Res. 2005 Oct;297(4):147-53. Epub 2005 Oct 26. Erratum in: Arch Dermatol Res. 2006 Apr;297(10):481. In Finland, research has also found that the higher the amount of silicon in the drinking water, the lower the likelihood of developing heart disease. Schwarz K, Ricci BA, Punsar S, Karvonen MJ. Inverse relation of silicon in drinking water and atherosclerosis in Finland. For a review of silicon, see: Jurkić LM, Cepanec I, Pavelić SK, Pavelić K. Biological and therapeutic effects of ortho-silicic acid and some ortho-silicic acid-releasing compounds: New perspectives for therapy. However, silicon is an orphaned mineral, meaning there is no scientist who has dedicated his life’s work to silicon, that is, there is no silicon expert. So, if you have osteoporosis, remember there is much more to it than just vitamin D and calcium, as the open access article below summarizes.