Consuming vitamin K2 in its MK-7 form is better for raising levels of the vitamin in serum than K2 in the MK-4 form, says a new study from Japan and the Netherlands. The results indicate that the “nutritional values of vitamin K2 homologues should be differentiated with regard to bioavailability and efficacy,” wrote scientists from J-Oil Mills, Inc., in Japan, University Maastricht in The Netherlands, and Kagawa Nutrition University in Japan in the Nutrition JournalThere are two main forms of vitamin K: phylloquinone, also known as phytonadione, (vitamin K1) which is found in green leafy vegetables such as lettuce, broccoli and spinach, and makes up about 90% of the vitamin K in a typical Western diet; and menaquinones (vitamins K2), which make up about 10% of Western vitamin K consumption and can be synthesised in the gut by microflora.Menaquinones (MK-n: with the n determined by the number of prenyl side chains) can also be found in the diet; MK-4 can be found in animal meat, MK-7, MK-8, and MK-9 are found in fermented food products like cheese, and natto is a rich source of MK-7.“
Because all vitamin K homologues can be converted to MK-4 in vivo, MK-4 is considered to have specific functions other than gamma-carboxylation of vitamin K-dependent proteins,” explained the researchers.“In this study, we demonstrated that a nutritional dose of MK-7 is well absorbed in human, and significantly increases serum MK-7 levels, whereas MK-4 had no effect on serum MK-4 levels. The researchers tested the effects of a single dose of MK-4 (420 micrograms) or MK-7 (420 micrograms) consumed with a standardized breakfast in ten health Japanese women. Results showed that MK-7 was well absorbed and was measurable in serum samples up to 2 days after consumption.On the other hand, MK-4 was not measured in any of the women at any time, they said.A second study that used consecutive administration of MK-4 (60 micrograms) or MK-7 (micrograms) for seven days again with ten health Japanese women indicated that MK-4 again did not increase MK-4 levels. On the other hand, MK-7 was found to increase MK-7 levels.“
The current study shows that MK-4 has a poor bioavailability at a nutritional level dose, whereas MK-7 is well absorbed and detectable in the blood at nutritional levels,” wrote the researchers.“In a previous rat study from our group [Vitamins (Japan) 2007, Vol. 81, pp. 377-381], the intake of a nutritional dose of MK- 4 did not increase the MK-4 levels in extrahepatic tissues, whereas MK-7 significantly increased MK-4 in extrahepatic tissues,” they added.“Thus, MK-7 is a better supplier for MK-4 in vivo than MK-4 itself.” “Comparison of menaquinone-4 and menaquinone-7 bioavailability in healthy women”Authors: T. Sato, L.J. Schurgers, K. Uenishi “You’re Only as Old as Your Arteries”… Isn’t It Time You Gave Them Your Attention?" According to researchers, the state of your arteries – or your “vascular age” – may be a much better indicator of your health and longevity than your actual age. Label Snapshot for Vitamin K2Vitamin D Spray Vitamin K (Vitamin K2)
OTHER INGREDIENTS: Microcrystalline Cellulose, Glycerol Monostearate, Capsule (Hydroxypropyl Methylcellulose), Ascorbyl Palmitate, Rosemary Leaf Extract. SUGGESTED USE: Adults, as a dietary supplement, take one (1) capsule daily with a meal. Vitamin D (Vitamin D3) OTHER INGREDIENTS: Water, Cellulose, Natural Flavors, Medium Chain Triglycerides, Xanthan Gum, Citric Acid, Potassium Sorbate (to Maintain Freshness), Stevia (Stevia rebaudiana [Bertoni]) (Leaf) Extract, Mixed Tocopherols, Rosemary (Leaf) Extract. SUGGESTED USE: Adults, as a dietary supplement, shake before use, and take five (5) sprays daily. For best results, refrigerate after opening. Before first use, break tab in front, push in child resistant lock and turn to right to unlock. Shake well and press actuator down 3 more times to prime pump. MSRP: $102.99 Your Price: $69.97 Savings: $33.02 (32%) Vitamin K2 90 Capsules and Vitamin D Spray 3-Pack (1) Vitamin K2 (90 Capsules) (3) Vitamin D Spray (0.85 fl oz)
MSRP: $162.99 Your Price: $106.97 Savings: $56.02 (34%) Vitamin K2 and Vitamin D Spray (1) Vitamin K2 (30 Capsules) (1) Vitamin D Spray (0.85 fl oz) MSRP: $54.95 Your Price: $36.97 Savings: $17.98 (32%) Out of Stock Notice: Due to high demand, these products are temporarily out of stock. We expect to have a supply soon, so please keep posted. !Vitamin K2 capsules (30 per bottle): 30 Day Supply MSRP: $34.99 Your Price: $27.97 Savings: $7.02 (20%) I am so confident that you will be more than satisfied with your purchase of this product, I am providing you with a Money Back Guarantee on returned items. Click here for full return policy details MON - FRI (7am - 8pm CST) | SAT - SUN (8am - 5pm CST) Top 5 Frequently Asked Questions Vitamin K2 30 Capsules Vitamin K2 90 Capsules Two forms of vitamin K2 are typically found in supplements: MK-4 (synthetic) and MK-7 (natural, from natto). There are significant differences between them: in paticular, MK-7 has a longer half-life, so a smaller dose can be used.
Two newer forms of MK-7 are available that are synthetic. Get the details in the Review of Vitamin K Supplements, which includes our tests and comparisons of products containing both forms of K2 as well as vitamin K1. See other recent and popular questions >>We read all questions and try to answer those of popular interest. Add to Wish List Expiration Date: Jul 2018 Package Quantity: 60 Softgels Madre Labs, EPA 850 Fish Oil, Pharmaceutical Grade, German Processed, No GMOs, No Gluten, 1000 mg, 30 Fish Gelatin Softgels Add Both to Cart Jarrow Formulas MK-7 is made via fermentation by Bacillus subtilis natto. MK-7 (Menaquinone-7) is an enhanced bioactive form of vitamin K2 found naturally occurring in Natto that is ten times better absorbed than K1 from spinach. MK-7 is responsible for the carboxylation of specific bone proteins needed for building bones. Take 1 softgel per day or as directed by your qualified healthcare professional. Non-GMO medium chain triglycerides, evening primrose oil and non-GMO soybean oil.
Softgel consists of gelatin, glycerin, water and caramel (as a light barrier). No wheat, no gluten, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts. Note: If you have a medical condition, are pregnant, lactating, or trying to conceive, under the age of 18, or taking medications (especially anticoagulants [e.g. warfarin/Coumadin]), consult your healthcare professional before using this product. Keep out of the reach of children. Serving Size: 1 Softgel Servings Per Container: 60 MK-7 (Vitamin K2 as Menaquinone-7) (from non-GMO Natto Extract) *Daily Value not established. Posted by paochi on Mar 07, 2017I will buy again. Was this review helpful to you? Posted by 4625330869081975517 on Feb 19, 2017 I have been using this now about 1 year. It's time to take a little break. Posted by Reviewer2813819 on Feb 17, 2017 Jarrow- vitamin k2mk7 vitamin Posted by 5617393212218700420 on Feb 06, 2017 Bone health-I take this with vitamin D3, and my hip pain has disappear.