To implant successfully your uterus, an embryo needs rich, nourishing uterine lining – not too thick and not too thin. Low estrogen, scar tissue from D&C procedures, fibroids and other issues can cause your uterine lining to thin out, or prevent your uterus from getting the blood flow it needs to thicken up. As a result, egg implantation is difficult. Your doctor may suspect thin uterine lining if you’re having trouble getting pregnant and have one (or more) of these traits: a condition that affects blood flow to the uterus, such as fibroids or a “tilted uterus” a condition that affects the health of your endometrial tissue, such as pelvic inflammatory disease or scar tissue (Asherman’s syndrome) If your endometrial thickness (ET) is less than 7mm, embryo implantation may be hard. There are reported pregnancies for embryo transfers into a uterine lining as little as 4mm, but it’s so unreliable and risky that we generally recommend freezing your embryos and waiting for a thicker endometrium in a future cycle instead of transferring them right off the bat.
Of course, that advice isn’t very helpful if your ET is always less than 7. Here are steps we take to improve your ET thickness – but remember that not all of these steps will be right for you, and that you should give any lifestyle change (e.g. exercise) or interventions (acupuncture, vitamins) 2 months minimum and 6 months maximum before expecting results. Maximize your natural blood flow with acupuncture or regular, moderate exercise. Higher blood flow should bring more egg-friendly nutrients to your uterine lining. Minimize anything that could hurt your blood flow. Try cutting caffeine to one cup (or less!) per day, not smoking, and avoiding seasonal allergy meds or over-the-counter cold remedies that stop nasal swelling. (Don’t worry, regular or extra-strength Tylenol are fine.) Take estrogen – either exogenously (oral tablets, vaginal tablets, patches) or endogenously (rFSH treatments like Gonal F and Puregon). Put on some weight: it’s great at promoting pelvic blood flow.
You’ll want a BMI over 18.4, and ideally over 19.0. In other words, a little weight gain is a good thing – those fat cells generate natural estrogens. Talk to a nutritional counselor for advice. Don’t rule out folklore. Because this condition hasn’t been heavily researched, we don’t know everything yet. Increasing your red meat intake to 1-2 times a week or drinking red raspberry leaf tea are both seemingly harmless suggestions that may assist you. Don’t rule out scientific hunches either. These supplements aren’t proven as effective, but might help: antioxidants like vitamin C (up to 1000mg/day) or vitamin E (up to 400IU/day), or CoEnzyme Q10 up to 800mg/day. There are also experimental approaches out there, but they may or may not be available, and definitely aren’t guaranteed to work: Trental 400mg three times daily with Vitamin E 400iu once daily during pretreatment (birth control pill or barrier contraception cycles) Know a useful resource on this topic?
Send us your suggestion!Without vitamin E the body cannot reproduce. A study performed in 1922 showed that rats whose diet was devoid of vitamin E became infertile. Once they were given wheat germ oil (rich in vitamin E) as part of their diet, the rat’s fertility was restored. Today, research shows vitamin E is essential in protecting and improving cellular health. Each and every part of the body is made up of trillions of cells, including the reproductive organs, the egg and the sperm. Alpha-tocopherol is the chemical name for the most active form of vitamin E. The term tocopherol comes from the Greek words tokos, which means “offspring,” and phero, which means “to bear”. Tocopherol literally means “to bear children”. Clearly vitamin E is essential to healthy fertility. Vitamin E functions primarily as an antioxidant, protecting cell membranes from oxidative damage. It has been shown especially effective for protecting nerve cells, red blood cells, and immune system function;
aiding in the prevention of and healing of neurological disorders, chronic viral illness and anemia. Several studies have been performed in relation to fertility health, revealing its importance for reproductive function and health. Vitamin E is incorporated into the lipid (fatty) part of the cell membrane, where it stabilizes and protects the cell membrane from toxic compounds including lead, mercury and other heavy metals; toxic compounds such as benzene, carbon tetrachloride, cleaning solvents (all known endocrine disruptors); This is especially important for hormonal balance, as well as cellular health. Toxic compounds have been shown to contribute to infertility. Vitamin E deficiency is rare, but there are some conditions in which low levels are common: Increased Thickness For Thin Uterine Lining A study published by Fertility and Sterility in April, 2010, showed that vitamin E supplementation may aid in increasing the thickness of the endometrium in women with thin uterine lining <8mm. Researchers wanted to see if these supplement could increase uterine radial artery (uRA) blood flow.
E given at 600mg a day increased uRA in 72% of patients and endometrial thickness (EM) in 52% of patients. Improved Sperm Health and Motility, Reduction in Miscarriage Studies have shown that vitamin E increases sperm health and motility. In one study it was shown that sperm motility, percent of live sperm, and percent of normal spermatozoa all increased with the supplementation of vitamin E and selenium. As mentioned previously, a study performed on rats whose diet was devoid of vitamin E, showed those rats to become infertile. This study showed male rat’s sperm became immobile and female rats had a higher rate of miscarriages than rats who were not vitamin E deficient. The rats were then given wheat germ oil which is high in vitamin E and their fertility was completely restored. Improved Glucose Metabolism and Insulin Activity for PCOS and Diabetes Oxidative stress is a major concern for women who are trying to conceive and have either insulin resistant PCOS or diabetes.
Vitamin E supplementation has been shown to improve insulin action. One study showed that non-insulin taking, otherwise healthy diabetics who took 1,310 IU of vitamin E for 4 months had improved glucose tolerance and insulin sensitivity. The researchers conclusion was that the vitamin E supplementation reduces oxidative stress, improving cell membrane physical characteristics and related activities in the transport of glucose. Speak with your doctor prior to using vitamin E at higher levels as part of a diabetes management plan. Reduction in PMS Symptoms and Fibrocystic Breast Disease Several double-blind clinical studies have been performed on vitamin E (alpha-tocopherol) supplementation for the reduction of fibrocystic breast disease and premenstrual syndrome (PMS). Premenstrual syndrome is cyclic and comes with many uncomfortable symptoms including, painful swelling of the breasts, bloating, water retention, cramping, headache, dizziness, foggy thinking, irritability and depression.
Fibrocystic breast disease are benign tumors of the breast and often become painful and swollen with the onset of menstruation. These studies indicate that women given 600 IU of vitamin E per day had a reduction in overall PMS symptoms, particularly fibrocystic breast disease. It appears the vitamin E normalizes hormone levels in both PMS and FBD patients. Increased Success Rate for IVF In another study, it has been shown that men who prepared with vitamin E prior to IVF treatment, with their partners, had an increase in rate of fertilization from 19% to 29%. Vitamin E in amounts up to 600 IU per day (use only 50 IU if you have high blood pressure, heart disease, or diabetes) has been shown to help prevent miscarriage in women with a history of recurrent miscarriage. Supports a Healthy Amniotic Sac in Pregnancy Vitamin E supplementation has been shown to help prevent premature rupture of the membranes (amniotic sac) in pregnancy. It appears that vitamin E may increase the quality of the amniotic sac.
First and foremost vitamin E should be consumed by eating a diet rich in a variety of different whole foods. Foods that are rich in vitamin E are: Raw vegetable oils, nuts, nut butters, rice bran oil, barley, seaweed, green leafy vegetables, asparagus, avocado, berries, and tomatoes. As you learned before, vitamin E is an antioxidant. Antioxidants help protect protect the body from the damage caused by free radicals. Antioxidants neutralize the free radicals, stopping further damage from happening and protecting the cells health, but the body needs a variety of antioxidants to do this. Antioxidants work to stop free radicals by engulfing them, and then melding into its molecular structure. Antioxidants rely on other “sister” antioxidants to come and revive them, so they can continue on to stop free radicals from spreading and damaging cells. CoQ10, vitamin C and Lipoic Acid revive vitamin E. In order to be sure you are getting a wide variety of antioxidants, we suggest you supplement with a complete antioxidant supplement to protect cellular health.
There are a variety of different forms of vitamin E. If you choose to supplement with vitamin E, be sure you are first getting it through whole foods and second choose natural sources, never synthetic. There are several other natural tocopherols that demonstrate vitamin E activity and exert antioxidant activity, they are: d-beta-, d-gamma-, d-delta-, and a group of related compounds known as tocotrienols. These are not as strong as d-alpha, but still beneficial. Suggested daily usage: 500mg a day of mixed tocopherols and tocotrienols in addition to a diet rich in vitamin E foods. 1. Murray, Michael T., N.D. (1996).Encyclopedia of Nutritional Supplements The Essential Guide for Improving Your Health Naturally. 2. Takasaki A, Tamura H, Miwa I, Taketani T, Shimamura K, Sugino N (April 2010). “Endometrial growth and uterine blood flow: a pilot study for improving endometrial thickness in the patients with a thin endometrium”. 3. Keskes-Ammar, L., Feki-Chakroun, N., Rebai, T., Sahnoun, Z., Ghozzi, H., Hammami, S., … & Bahloul, A. (2003).