"Osteoarthritis (OA) also known as degenerative arthritis or degenerative joint disease, is a group of mechanical abnormalities involving degradation of joints,1 including articular cartilage and subchondral bone. Symptoms may include joint pain, tenderness, stiffness, locking, and sometimes an effusion. A variety of causes—hereditary, developmental, metabolic, and mechanical—may initiate processes leading to loss of cartilage. When bone surfaces become less well protected by cartilage, bone may be exposed and damaged. As a result of decreased movement secondary to pain, regional muscles may atrophy, and ligaments may become more lax.2" "Often, the cause of OA is unknown. It is mainly related to aging. The symptoms of OA usually appear in middle age. Almost everyone has some symptoms by age 70. However, these symptoms may be minor. Before age 55, OA occurs equally in men and women. After age 55, it is more common in women." Pages listed in BOTH the categories Bone and Magnesium
MAGNESIUM IN MAN - IMPLICATIONS FOR HEALTH AND DISEASE – review 2015 Stronger bones after 3 generations of tap water (more Ca and Mg) vs bottled water – March 2015 Bones grow better with high level of magnesium: rat study – Dec 2013 20 percent fewer male hip fractures if more Magnesium in the water – July 2013 Magnesium may be more important to kids’ bone health than calcium – May 2013 Healthy bones need: Calcium, Vitamin D, Magnesium, Silicon, Vitamin K, and Boron – 2012 Vitamin D, K2, Magnesium, etc increase bone density when taking together– Jan 2012 400 IU of vitamin D Magnesium and Calcium helped Twin bones – Feb 2011 Pages listed in BOTH the categories Bone and Vitamin K2 Better bones again associated with higher vitamin K intake – Nov 2015 Increased Vitamin K2 reduces the problems of excess Calcium – Nov 2013 Vitamin K-2 (180 ug MK-7) helped both bone density and strength – RCT March 2013 Healthy bones need Ca, Silicon, Vitamins B, C, D, and K – Dec 2012
Increasing bone mineral density increases breast cancer by at least 2X – Aug 2012 BONE SPURS not produced if have enough Vitamin D3, Vitamin K2, etc. – Nov 2011 Vitamin K1 reduced hip fracture but Vitamin K2 did not – Aug 2011 Women with hip fractures very low on vitamins D3 and K – Mar 2011 Vitamin K2 from natto improved bone mineral density – March 2011 During Spring/Summer of 2014 (age 68) I got sharp pain below both knees - which my Dr. diagnosed as early indication of OA. Tried a shotgun of 7 solutions (in addition to vitamin D) and the pain went away for several weeks Stopped all solutions and the pain returned in a few days (still had vitamin D) Restarted with just a subset of solutions - and have had no pain at all for the past 10 days Note: Magnesium: it helps muscles see Wikipedia Magnesium in biology and Magnesium deficiency (medicine) Also see Overview Magnesium and vitamin D I got back into Feldekrais exercises every 4 days (which I have used for 30+ years) to restore flexibility, muscle strenth, and use of different muscles to accomplish the same movement.
Restorative Effect of Vitamin D Deficiency on Knee Pain and Quadriceps Muscle Strength in Knee Osteoarthritis 25-Hydroxyvitamin D and osteoarthritis: A meta-analysis including new dataEpub 2010 Dec 30. CONCLUSION: Sunlight exposure and serum 25(OH)D levels are both associated with decreased knee cartilage loss (assessed by radiograph or MRI). This is best observed using the whole range of 25(OH)D levels rather than predefined cut points and implies that achieving vitamin D sufficiency may prevent and/or retard cartilage loss in knee OA. PMID: 19404958 CLICK HERE for full article J Orthop Sci. 2009 Nov;14(6):687-92. Epub 2009 Dec 8. RESULTS: The prevalence of knee OA of KL >or=2 was 70.8%. Age, body mass index, and female sex were positively associated with the prevalence. Among the dietary factors, only vitamin K intake was shown to be inversely associated with the prevalence of radiographic knee OA by multivariate logistic regression analysis. The presence of joint space narrowing of the knee was also inversely associated with vitamin K intake.
The prevalence of radiographic knee OA for each dietary vitamin K intake quartile decreased with the increased intake. CONCLUSIONS: The present cross-sectional study using a population-based cohort supports the hypothesis that low dietary vitamin K intake is a risk factor for knee OA. Vitamin K may have a protective role against knee OA and might lead to a disease-modifying treatment. Graph of treatments people with OA use - notice frequent use of Calcium It appears that Meloxicam = mobic Rheumatology, Volume 52, Issue 7, Pp. 1323-1334. Graeme Jones 1 and Changhai Ding 1,4 changhai.ding at utas.edu.au 1 Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia, 2 Research Institute of Orthopedics, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China, 3 Institute of Bone and Joint, Peking University People’s Hospital, Peking, China and 4Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia.
To systematically review the evidence for association between serum 25-hydroxyvitamin D (25-(OH)D) and OA and the effect of vitamin D therapy on OA.An English Medline, EMBASE and Cochrane Library search for vitamin D and OA from January 1980 to June 2012 was performed. Randomized controlled trials (RCTs), cohort, case–control and cross-sectional studies in adults were included. The methodological quality of the selected studies was assessed and a best-evidence synthesis was used to summarize the results due to the heterogeneity of the studies.Of the 86 evaluated articles, 2 RCTs and 13 observational studies were included in the final analyses. The number of participants ranged from 64 to 1644 (0–100% women). The RCTs were only reported in abstract form and showed inconsistent results, most likely due to variations in their study design. There was insufficient or limited evidence for associations between 25-(OH)D and hand or hip OA. For knee radiographic OA as assessed by the Kellgren and Lawrence (KL) score, there was moderate evidence showing that low levels of 25-(OH)D were associated with increased progression of radiographic OA.