Use for nutritional assessment of vitamin B6. Collect specimen after an overnight fast. Green (sodium or lithium heparin) or plasma separator tube. Also acceptable: Plain red. Protect from light during collection, storage, and shipment. Separate plasma or serum from cells within 1 hour of collection. Transfer 1 mL plasma or serum to an ARUP Amber Transport Tube. Any specimens other than heparinized plasma or serum. Serum separator tubes or EDTA preserved tubes. Specimens not protected from light. After separation from cells: Ambient: Unacceptable; Pyridoxal 5'-phosphate measured in a specimen collected following an 8 hour or overnight fast accurately indicates vitamin B6 nutritional status. Non-fasting specimen concentration reflects recent vitamin intake. Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use.
The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. Component Test Code*Component Chart NameLOINC0080111Vitamin B6 (Pyridoxal 5-Phosphate)2900-9 Vitamin B6 (Pyridoxal 5-Phosphate) Certain tests have specimen requirements that differ for specimens shipped from New York state. When available, show New York specimen requirements by default? Send to multiple recipients by separating addresses with a semicolon. Test Number / Name Test Number / Mnemonic Test Number / NameIt looks like your web browser's cookies aren't enabled. , you'll need to change your web browser settings to enable cookies. It's easy to fix this! Just click the help page to learn how to enable cookies. You can also place your order over the phone by dialing (800) 381-0759. Vitamins & SupplementsLetter VitaminsVitamin DVitamin D3 - Cholecalciferol Vitacost Vitamin D3 (as Cholecalciferol) -- 1000 IU - 200 Capsules
Shipping Weight: 0.18 lb Now & Every 15 Days Now & Every 30 Days Now & Every 45 Days Now & Every 60 Days Now & Every 90 Days Now & Every 120 Days Add to My List Added to My List as a guest*. *Your guest list will be temporarily saved until you end this browser session. 1 item added to your listSomething went wrong and we were unable to process your request. Spend $25 or more on Vitacost brand products and get FREE SHIPPING! Ideal form of vitamin D supports maintenance of healthy bones and teeth, cellular function and proper functioning of the immune and nervous systems.* What is vitamin D? Vitamin D is a fat-soluble vitamin that is naturally present in very few food sources. Its functions in the body are wide ranging, from contributing to bone health to supporting immune function. Vitamin D3 (cholecalciferol) is the same form of vitamin D that the body manufactures when skin is exposed to ultraviolet (UV) radiation from the sun.
Vitamin D3 may be more than three times as effective in raising concentrations of vitamin D in the bloodstream and maintaining those levels for a longer time.* How does vitamin D support health? Why choose Vitacost Vitamin D3? Vitacost nutritional products are manufactured to high standards of quality, efficacy and safety. Each Vitacost product meets or exceeds the standards and requirements set forth in the FDA’s Code of Federal Regulation (21 CFR, 111) Current Good Manufacturing Practices (CGMP). *These statements have not been evaluated by the Food and Drug Administration. As a dietary supplement, take 1 capsule with food daily, or as directed by a healthcare professional. Store in a cool, dry place. (NSI Vitamin D3 -- 1,000 IU - 200 Caps):Milk, eggs, peanuts, tree nuts, shellfish, fish, soy, gluten, titanium dioxide. These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.
Amount Per Serving% Daily Value Vitamin D3 (as cholecalciferol)1000 IU250% Pregnant or lactating women, diabetics, hypoglycemics, and people with known medical conditions and/or taking drugs should consult with a licensed physician and/or pharmacist prior to taking dietary supplements. Vitacost Vitamin D3 2000 IU with Probiotics -- 1 billion CFU** - 60 Tablets Vitacost Vitamin D3 Gummies for Adults -- 2000 IU - 60 Gummies Vitacost Vitamin D3 with Cultured Nutrients Organic Fruits & Vegetables -- 2000 IU - 60 Vegetarian CapsulesMolina has established Molina Clinical Policy that function as one of the sets of guidelines for coverage decisions or determinations. In this site, the Molina Clinical Policy is made accessible to you to guide you in your medical decisions. Please know that these Clinical Policies do not constitute plan authorization, nor is it an explanation of benefits.ICD-9-CM:268.0 - Rickets, Active268.2 - Osteomalacia, Unspecified268.9 - Vitamin D Deficiency, Unspecified;
Vitamin D deficiency is a nutritional disorder characterized in adults by softening of the bones. In children it manifests as rickets and in adults as osteomalacia. Vitamin D is an essential nutrient that increases serum calcium levels by facilitating calcium absorption and mobilizing calcium from bone. It also absorbs calcium and phosphorous from the diet. Without vitamin D, these minerals are not absorbed in sufficient quantities. Because calcium and phosphorous are important in forming and maintaining healthy bones and teeth, a deficiency in vitamin D has a profound effect on these structures. Vitamin D deficiency is a relatively rare condition since it is found in many foods such as fortified milk, margarine, eggs, liver, fish, and fish oils. The body can also make vitamin D when the skin is exposed to sunlight. A lack of vitamin D in the diet is usually only seen in strict vegetarians (vegans) who avoid all animal products including dairy products and eggs. Individuals who avoid exposure to sunlight or wear protective sunscreen may limit the body's ability to make vitamin D, thereby increasing the need to rely on dietary sources.
Another cause of vitamin D deficiency is an inability of the body to absorb the vitamin during digestion (malabsorption) or an inability to process the vitamin once it is absorbed. These individuals may experience a deficiency despite a healthy, balanced diet and normal sun exposure. Certain medications used to treat seizures can also cause vitamin D deficiency. The recommended daily allowance (RDA) for vitamin D is 400 IU.Incidence and Prevalence: The overall incidence of osteomalacia is 1 in every 1,000 individuals. Pregnancy and breastfeeding increase a woman's need for vitamin D and therefore increase the risk of deficiency. Women are affected slightly more often than men.The risk of developing osteomalacia is higher in those who are housebound, institutionalized, elderly, poor, or required by custom to be completely covered when outdoors. Those with dark skin are also at increased risk. Certain diseases of the kidney, pancreas, liver, intestines, or stomach may also increase the risk of vitamin D deficiency.
Alcoholics, individuals with eating disorders such as anorexia nervosa or bulimia nervosa, and those who follow diets that severely limit certain foods (fad diets) have a greater risk of developing vitamin D deficiency. Individuals who abuse laxatives are also at increased risk.History: Individuals may complain of bone pain particularly around the hips. Muscle weakness is also commonly reported. Some individuals may feel such discomfort and weakness that they choose to remain in bed. Fracturing bones after only minor trauma is also significant history. Individuals may report other symptoms such as tiredness (fatigue), muscle pain, loss of appetite (anorexia), unintentional weight loss, numbness around the mouth, tingling and/or numbness of the extremities (hands, arms, legs, feet), or muscle spasms (tetany) of the hands or feet. Lack of calcium can also cause confusion, memory loss, depression, and hallucinations.Physical exam: The exam may reveal that the individual has lost inches in height due to collapse of the vertebrae.
Reported bone pain is usually dull and spread over a large area (diffuse). Muscle weakness may be evident in the muscles close to the affected bone(s). Questioning the individual on dietary habits may reveal a lack of food sources that are typically rich in vitamin D. Further questioning may also reveal that the individual avoids being outdoors or carefully applies sunscreen before leaving the house.Tests: Routine blood tests reveal abnormal levels of calcium and phosphate. An x-ray and/or CT of the bone(s) confirm the diagnosis. In most cases, these tests in combination with symptoms and history is sufficient for a definitive diagnosis, however, in unusual cases, a bone biopsy may be necessary to determine the extent of the mineral loss.When vitamin D deficiency is caused by lack of sunlight or poor diet, individuals are given oral vitamin D supplements for up to 4 months. Calcium supplements may also be given. If the deficiency is due to an underlying condition that prevents absorption or metabolism of vitamin D, successful treatment depends on treatment of the underlying condition.
These individuals may require larger doses of vitamin D as well as megadoses of calcium. Depending on the nature of the underlying disease, these supplements may need to be given by injection. Controlled exposure to sunlight or a sunlamp may also be prescribed. Treatment for osteoporosis may also be needed. All individuals require regular follow-up visits with their doctor to monitor progress.Individuals whose deficiency is due to inadequate sunlight or poor diet are usually completely cured after 6 months of vitamin D supplements and/or sunlight exposure. If an underlying condition is causing or contributing to vitamin D deficiency, this disorder must be treated for a successful outcome. plications of vitamin D deficiency include bone fractures, infection of the bones (osteomyelitis), kidney (renal) failure, renal tubular acidosis, or seizures. In addition, individuals are often deficient in other vitamins and/or minerals as well as vitamin D, complicating the condition.In most cases, work restrictions and accommodations are not necessary.
For some individuals, heavy lifting and other strenuous work may need to be discontinued or adjusted. Work schedule flexibility may be required following the diagnosis to accommodate regular examinations at the physician's office. However, if symptoms are severe, individuals may require extended sick leave from work until symptoms begin to subside.Regarding diagnosis:Has individual complained of bone pain (particularly in the hips) or fatigue and paresthesias of fingers or hands? Does individual have risk factors for vitamin D deficiency such as inadequate consumption of dairy products (such as vegans, or those with lactose intolerance or those who do not have access to dairy products)? Has individual been housebound or lacked exposure to sunlight? Are they taking any medications that could cause the deficiency? Was the vitamin deficiency detected with serological testing? If not, was a bone biopsy indicated? If the diagnosis was uncertain, were other conditions with similar symptoms such as osteoporosis, Paget's disease of bone, and cancer, ruled out?
Regarding treatment:Were vitamin D and/or calcium supplements prescribed? Is individual taking the recommended dose at the recommended times? Is individual eating a healthy, balanced diet? Are foods rich in vitamin D being consumed? Would individual benefit from consultation with a nutritionist/dietitian? Does individual spend time outdoors or in a sunny window? Is individual also being treated for osteoporosis?Regarding prognosis:Based on the underlying cause, what was the expected outcome? Is individual a strict vegetarian? Does individual have any underlying conditions (malnutrition, pregnancy or epilepsy) that could impact recovery? Did individual experience any associated conditions or complications (such as bone fractures, osteomyelitis, renal disorders, or seizures) that could impact recovery and prognosis?GeneralBeers, Mark H., et al., eds. "Vitamin D Deficiency and Dependency." Merck Manual of Medical Information. 2nd Home Online ed. New York: Pocket Books, 1997.