*Product image may differ from product received. Vitamin A palmitate is the ester of retinol (vitamin A) and palmitic acid, a major component of palm oil. Also known as retinyl palmitate, it is a synthetic alternate for retinyl acetate in vitamin A supplements. The Vitamin A molecule is very unstable by itself. To create a more stable configuration, it is reacted with methyl palmitate. Vitamin A palmitate is used as an antioxidant and a source of vitamin A added to low-fat milk and other dairy products to replace the vitamin content lost through the removal of milk fat. Vitamin A helps form and maintain healthy teeth, skeletal and soft tissue, mucous membranes and skin. It is commonly known as the anti-infective vitamin. It is required for normal functioning of the immune system. It has antioxidant properties, offering protection to cell membranes that can be damaged by free radical molecules created during the body's oxidation process. Vitamin A is important for vision, where a deficiency in retinol results in impaired adaptation to darkness, known as night blindness.
*NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Tested by Accredited 3rd Party Labs This PureBulk product is manufactured in a cGMP registered facility. PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here. Supplement Facts & Directions Vitamin A (as Palmitate) 15500 IU310% * Percent Daily Values are based on a 2,000 calorie diet.† Daily Value Not Established ‡ These supplement facts may vary from the product you recieve. Please call for exact numbers. Other Ingredients: Dextrin, Modified Food Starch, & Sucrose. Soy, Dairy, Yeast & Gluten. As a dietary supplement take 60 mg daily, or as directed by a physician. Accurate gram weight scale recommended.
Warning: If you are pregnant, nursing, taking any medications or have any medical condition consult your physician before use. *NOTE: These statements have not been evaluated by the Food and Drug Administration. Retinyl palmitate, or vitamin A palmitate, is the ester of retinol (vitamin A) and palmitic acid, with formula C36H60O2. An alternate spelling, retinol palmitate, which violates the -yl organic chemical naming convention for esters, is also frequently seen. Retinyl palmitate is a synthetic alternate for retinyl acetate in vitamin A supplements, and is available in oily or dry forms. It is a common vitamin supplement, available in both oral and injectable forms for treatment of vitamin A deficiency, under the brand names Aquasol A, Palmitate A and many others. It is a constituent of intra ocular treatment for dry eyes at a concentration of 138 µg/g (VitA-Pos) by Ursapharm. It is a pre-formed version of vitamin A; therefore, the intake should not exceed the Recommended Dietary Allowance (RDA).
Overdosing preformed Vitamin A forms such as retinyl palmitate leads to adverse physiological reactions (hypervitaminosis A). Retinyl palmitate is used as an antioxidant and a source of vitamin A added to low fat milk and other dairy products to replace the vitamin content lost through the removal of milk fat. Palmitate is attached to the alcohol form of vitamin A, retinol, in order to make vitamin A stable in milk. Retinyl palmitate is also a constituent of some topically applied skin care products. After its absorption into the skin, retinyl palmitate is converted to retinol, and ultimately to retinoic acid (the active form of vitamin A present in Retin-A). The Environmental Working Group (EWG) and New York Senator Chuck Schumer have called attention to the fact that high doses of topical retinyl palmitate were shown to accelerate cancer in lab animals,[2] fueling the sunscreen controversy in the popular press.[3] One toxicological analysis determined that "there is no convincing evidence to support the notion that [retinyl palmitate] in sunscreens is carcinogenic."
[4] EWG disputed the findings, calling the report "faulty" and "misleading."[5] A technical report issued thereafter by the National Toxicology Program concluded that diisopropyl adipate increased incidence of skin tumors in mice, and the addition of either retinoic acid or retinyl palmitate both exacerbated the rate and frequency of tumors. World Health Organization recommendation on Maternal Supplementation During Pregnancy states that "health benefits are expected for the mother and her developing fetus with little risk of detriment to either, from a daily supplement not exceeding 10,000 IU [preformed] vitamin A (3000 µg RE) at any time during pregnancy."[7] Preformed Vitamin A refers to retinyl palmitate and retinyl acetate. ^ Vitamin A, Linus Pauling Institute ^ National Toxicology Program. (2012). NTP technical report on the photocarcinogenesis study of retinoic acid and retinyl palmitate [CAS Nos. 302-79-4 (All-trans-retinoic acid) and 79-81-2 (All-trans-retinyl palmitate)] in SKH-1 mice (Simulated solar light and topical application study).
Accessed September 19, 2013.Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. Ships with any Subscribe & Save delivery. Detailsderma e Hydrating Night Crme with Hyaluronic Acid FREE Shipping on orders over . Detailsderma e Hydrating Eye Crème with Hyaluronic Acid and Pycnogenol, 1/2 Ounce, 14g FREE Shipping on orders over . 4-Ounce Jar - Packaging May Vary Enhance surface cellular renewal to diminish the appearance of age lines and wrinkles with this rich refining crème. Contains Vitamin A (Retinyl Palmitate) at a potency of 10,000 I.U. per 100 grams, commonly referred to as the "skin vitamin" and best known for its surface cell renewal properties.