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Nitrous oxide is the most durable of all inhaled anesthetics. Other agents have come and gone, but nitrous oxide has become even more popular. Today its applications in general anesthesia are nearly ubiquitous. Its widespread acceptance has resulted from many desirable properties: low solubility, limited cardiorespiratory depression, absent or minimal toxicity, and non-flammability. Such characteristics explain why nitrous oxide has outlasted its siblings, ether and chloroform.Contents:PrefaceAcknowledgmentsContributors1. A History of Nitrous Oxide2. Physics, Chemistry, and Manufacture of Nitrous Oxide3. Nitrous Oxide Analgesia4. MAC5. Nitrous Oxide Delivery Systems6. Pharmacokinetics7. Respiratory Effects of Nitrous Oxide8. Cardiovascular Effects of Nitrous Oxide9. Central Nervous System Effects of Nitrous Oxide10. Neuromuscular Effects of Nitrous Oxide11. Nitrous Oxide in Obstetrics12. Metabolism of Nitrous Oxide13. Nitrous Oxide Inactivates Methionine Synthetase14. Mutagenicity, Carcinogenicity, and Teratogenicity of Nitrous Oxide15. Nitrous Oxide Abuse16. Toxicity of Nitrous Oxide17. The Use of Nitrous Oxide by Dentists18. Nitrous Oxide in Veterinary Practice and Animal Research19. Controlling Occupational Exposure to Nitrous Oxide20. Should We Not Use Nitrous Oxide?21. We Should Continue to Use Nitrous OxideEpilogueIndex
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