Other name: Liposomal Ara-C Drug type: Cytarabine (Liposomal) is a sustained-releaseIt is an anti-cancer ("antineoplastic" or "cytotoxic")This medication is classified as an "antimetabolite." (For more detail, see "How this drug works" section below). Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful. Important things to remember about the side effects of cytarabine: The following side effects are common (occurring in greater than 30%) for patients taking liposomal cytarabine: These side effects are less common side effects (occurring in about 10-29%) of patients receiving liposomal cytarabine: Not all side effects are listed above, some that are rare (occurring in less than 10% of patients) are not listed here. However, you should always inform your health care provider if you experience any unusual symptoms. Contact your health care provider immediately, day or night, if you
should experience any of the following symptoms: The following symptoms require medical attention, but are not an emergency. Contact your health care provider within 24 hours of noticing any of the Always inform your health care provider if you experience any unusual symptoms. You will be checked regularly by your doctor while you are taking liposomal cytarabine, to monitor side effects and check your response to therapy. work to monitor your complete blood count (CBC), the function of other organs (such as your kidneys and liver) and check your uric acid levels will also be ordered Cancerous tumors are characterized by cell division, which is no longer controlled as it is in normal tissue. "Normal" cells stop dividing when they come into contact with like cells, a mechanism known as contact inhibition. cells lose this ability. Cancer cells no longer have the normal checks and balances in place that control and limit cell division.
The process of cell division, whether normal or cancerous cells, is through the cell cycle. cell cycle goes from the resting phase, through active growing phases, and then The ability of chemotherapy to kill cancer cells depends on its ability to haltUsually, the drugs work by damaging the RNA or DNA that tells the cell how to copy itself in division. If the cells are unable to divide,The faster the cells are dividing, the more likely it is that chemotherapy will kill the cells, causing the tumor to shrink. They also induce cell suicide Chemotherapy drugs that affect cells only when they are dividing are called cell-cycleChemotherapy drugs that affect cells when they are at rest are calledThe scheduling of chemotherapy is set based on the type of cells, rate at which they divide, and the time at which a given drug is likely to be effective. This is why chemotherapy is typically given in cycles. Chemotherapy is most effective at killing cells that are rapidly dividing.
Unfortunately, chemotherapy does not know the difference between the cancerous cells and the normal cells. The "normal" cells will grow back and be healthy but in the meantime, side effects occur. The "normal" cells most commonly affected by chemotherapy are the blood cells, the cells in the mouth, stomach and bowel, andresulting in low blood counts, mouth sores, nausea, diarrhea,Different drugs may affect different parts of the body. Cytarabine belongs to the category of chemotherapy called antimetabolites. Antimetabolites are very similar to normal substances within the cell. the cells incorporate these substances into the cellular metabolism, they are unableAntimetabolites are cell-cycle specific. at very specific phases in the cycle. Antimetabolites are classified according to the substances with which they interfere. Note: We strongly encourage you to talk with your health care professional about your specific medical condition and treatments.
contained in this website is meant to be helpful and educational, but is not a substitute is designed to provide the latest information about chemotherapy to patients and their families, caregivers and friends. NBC accuses Republicans of accepting bad “science” on vaccines, while Fox News fires back, accusing liberals of spreading bad “science” on vaccines. Each side is trying to score partisan political points. The message from both sides is that vaccines are completely safe. But that message is absolutely and demonstrably false. As I noted in a recent column, the National Vaccine Injury Compensation Program exists to compensate victims of vaccines. The latest Statistics Report shows nearly 4,000 claims were awarded financial damages. Why do both sides of this “debate” pretend that vaccine-related injuries do not occur? Why not just report the facts? It doesn’t take a lot of work to dig them out. Barbara Loe Fisher of the National Vaccine Information Center (NVIC) tells me that she has given more than 100 interviews in the last two weeks on the subject of the measles outbreak, but that the media simply will NOT report on the existence of this federal program and the implications for the subject of vaccine safety.
“Vaccines are the only pharmaceutical products that government mandates and completely indemnifies,” she notes. She is referring to federal legislation that takes legal responsibility for their actions away from the companies making the vaccines. “I’ve been talking about it in every interview I do and I have been bringing it up. But whenever I talk about liability protection for the companies—that this is the only pharmaceutical product that is mandated by government and indemnified by government—they [the media] don’t want to talk about it,” she said. Observers believe the glaring omission reflects the power of pharmaceutical companies or their advertising agencies in the major media. It is in the interest of these companies to make pariahs out of those favoring vaccine choice by playing down—or even suppressing—questions about vaccine safety. Simply put, the evidence and history show that the vaccine makers have been given total liability protection for injuries and deaths caused by government-mandated vaccines.
Vaccine safety is not “settled science,” as we have been hearing repeatedly in the media. To the contrary, for purposes of the law, vaccines are considered sometimes unsafe, even deadly. The “Vaccine injury table” associated with the legislation includes a list of the injuries, disabilities, illnesses, conditions, and deaths resulting from the administration of such vaccines. But why is it so difficult for the media to report on the existence of these health problems? The vaccines that are covered include: As I reported in my column, the one exception to this drumbeat of misleading and inaccurate coverage about “vaccine safety” is on the local level, where correspondent Michael Chen of ABC 10 News in San Diego, California noted a case of a boy who suffered serious injuries, including fever, seizures, nervous tics and autism, as a result of two vaccines. The mother, almost in tears as she described what happened to her son, was paid $55,000 in damages through the federal program.
But the damage award didn’t cover the autism diagnosis. She said she wished she had more thoroughly researched the safety of vaccines. The National Vaccine Injury Compensation Program grew out of the 1986 National Childhood Vaccine Injury Act. Fisher explains what happened: “The companies threatened Congress that they were going to leave the people without any childhood vaccines if they did not get liability protection. The companies wanted this liability protection and it was mainly for losses at that time for DPT and oral polio vaccine. MMR (Measles, Mumps, and Rubella) vaccine at that point was a relatively new combination vaccine.” The DPT vaccine had been associated with brain inflammation and brain damage, while polio paralysis can be caused by the vaccine. Fisher explains what the federal protection means for the companies: “Nobody who makes or profits from the sale of the vaccine, nobody who regulates the vaccine, who promotes the vaccine, who votes to mandate the vaccine—nobody is accountable or liable in a civil court of law in front of a jury of our peers when we get hurt because we’ve been told we have to take it
, or when the vaccine fails to work.” The compensation program, with total liability protection for injuries and deaths caused by government-mandated vaccines, was upheld by the Supreme Court in a 2011 case in which vaccines were acknowledged to be “unavoidably unsafe.” My column actually underestimated the total financial damages paid through the program. The figure is actually $2.8 billion to the victims or the families of victims themselves. Liberal and conservative media are trying to make political points over who’s right and wrong about vaccine safety. But Fisher says people who support her group and vaccine choice come from across the political spectrum and include Democrats, Republicans, libertarians, and independents. In the media, however, each side is trying to smear the other side, as if there is a partisan divide. The coverage has led to cases of strange bedfellows, such as the George Soros-funded blog Think Progress running a story praising Megyn Kelly of Fox News under the headline, “Megyn Kelly Speaks Up For Mandatory Vaccination On Fox: ‘Some Things Do Require Big Brother.’”
Indeed, Kelly defended mandatory vaccines, saying, “…some things do require some involvement of Big Brother.” What she and many others in the media have consistently ignored is the role of Big Brother in shielding the companies making the vaccines from the side effects of their products. As I asked in my column: If there are no problems associated with vaccines, then why did Congress pass the National Childhood Vaccine Injury Act of 1986, which created a national Vaccine Injury Compensation Program? The media on the left and right have no answer to this question. So they pretend there is no debate or dispute over the safety of vaccines. They simply point fingers about one side or the other being guilty of ignoring what they pretend is settled science. The only thing “settled” about the science is that while vaccines work for a large majority of people, they can also cause serious health problems, even death, for some. The commentators who ignore the truth are either lying or so utterly ignorant that they should not be in a position of offering “news” on a national basis.