We're sorry, but we could not fulfill your request for /high-dose-vitamin-c-protocol-for-cancer/ on this server. An invalid request was received from your browser. This may be caused by a malfunctioning proxy server or browser privacy software. Your technical support key is: af29-b8ee-1756-6707 You can use this key to fix this problem yourself. and be sure to provide the technical support key shown above.Maybe Linus Pauling was on to something after all. Decades ago the Nobel Prize–winning chemist was relegated to the fringes of medicine after championing the idea that vitamin C could combat a host of illnesses, including cancer. Now, a study published online today in Science reports that vitamin C can kill tumor cells that carry a common cancer-causing mutation and—in mice—can curb the growth of tumors with the mutation. If the findings hold up in people, researchers may have found a way to treat a large swath of tumors that has lacked effective drugs.
"This [could] be one answer to the question everybody's striving for," says molecular biologist Channing Der of the University of North Carolina, Chapel Hill, one of many researchers trying to target cancers with the mutation. The study is also gratifying for the handful of researchers pursuing vitamin C, or ascorbic acid, as a cancer drug. Maybe people will finally pay attention," says vitamin C researcher Mark Levine of the National Institute of Diabetes and Digestive and Kidney Diseases. In 1971, Pauling began collaborating with a Scottish physician who had reported success treating cancer patients with vitamin C. But the failure of two clinical trials of vitamin C pills, conducted in the late 1970s and early 1980s at the Mayo Clinic in Rochester, Minnesota, dampened enthusiasm for Pauling’s idea. Studies by Levine’s group later suggested that the vitamin must be given intravenously to reach doses high enough to kill cancer cells. A few small trials in the past 5 years—for pancreatic and ovarian cancer—hinted that IV vitamin C treatment combined with chemotherapy can extend cancer survival.
But doubters were not swayed. "The atmosphere was poisoned" by the earlier failures, Levine says. A few years ago, Jihye Yun, then a graduate student at Johns Hopkins University in Baltimore, Maryland, found that colon cancer cells whose growth is driven by mutations in the gene KRAS or a less commonly mutated gene, BRAF, make unusually large amounts of a protein that transports glucose across the cell membrane. The transporter, GLUT1, supplies the cells with the high levels of glucose they need to survive. GLUT1 also transports the oxidized form of vitamin C, dehydroascorbic acid (DHA), into the cell, bad news for cancer cells, because Yun found that DHA can deplete a cell’s supply of a chemical that sops up free radicals. Because free radicals can harm a cell in various ways, the finding suggested “a vulnerability” if the cells were flooded with DHA, says Lewis Cantley at Weill Cornell Medicine in New York City, where Yun is now a postdoc. Cantley’s lab and collaborators found that large doses of vitamin C did indeed kill cultured colon cancer cells with BRAF or KRAS mutations by raising free radical levels, which in turn inactivate an enzyme needed to metabolize glucose, depriving the cells of energy.
Then they gave daily high dose injections—equivalent to a person eating 300 oranges—to mice engineered to develop KRAS-driven colon tumors. The mice developed fewer and smaller colon tumors compared with control mice. Cantley hopes to soon start clinical trials that will select cancer patients based on KRAS or BRAF mutations and possibly GLUT1 status. His group’s new study "tells you who should get the drug and who shouldn't," he says. Cancer geneticist Bert Vogelstein of Johns Hopkins University, in whose lab Yun noticed the GLUT1 connection, is excited about vitamin C therapy, not only as a possible treatment for KRAS-mutated colon tumors, which make up about 40% of all colon cancers, but also for pancreatic cancer, a typically lethal cancer driven by KRAS. “No KRAS-targeted therapeutics have emerged despite decades of effort and hundreds of millions of dollars [spent] by both industry and academia,” Vogelstein says. Others caution that the effects seen in mice may not hold up in humans.
But because high dose vitamin C is already known to be safe, says cancer researcher Vuk Stambolic of the University of Toronto in Canada, oncologists “can quickly move forward in the clinic." One drawback is that patients will have to come into a clinic for vitamin C infusions, ideally every few days for months, because vitamin C seems to take that long to kill cancer cells, Levine notes. But Cantley says it may be possible to make an oral formulation that reaches high doses in the blood—which may be one way to get companies interested in sponsoring trials.What does vitamin C accomplish? Vitamin C is a very powerful antioxidant. Many diseases are based on 'oxidative stress' which vitamin C can relieve by neutralizing free radicals present. Vitamin C has an anti-toxic effect in poisoning of any kind, from insect bites to snake venoms, but secondary bacterial and viral poisoning, too, can be successfully treated. It can also be used in sepsis ('blood poisoning'), or whenever side effects of chemical drugs such as ones used in chemotherapy tax the body.
Vitamin C is also successfully used in heavy metal intoxication. There is probably no known virus that cannot be successfully fought by vitamin C—in stark contrast to what is known in conventional medicine. Even severe life-threatening mushroom poisoning can be neutralized with vitamin C, provided that immediate intravenous administration is given. In cases of poisoning which does not require immediate and life-sustaining treatment, high doses of liposomal vitamin C can be used. What are the limits of vitamin C? For example, if poisoning has led to irreparable tissue damage, vitamin C cannot heal it. Vitamin C as a cure for cancer? For quite some time now, vitamin C in high doses has been used in alternative cancer therapies. It has been found that most cancer cells are very sensitive to vitamin C, and regress. A previously known reason for that is that vitamin C is similar in structure to glucose (sugar). Since cancer cells are very sugar-loving and need sugar for development and proliferation, vitamin C is taken up by them.
What exactly happens there? High doses of vitamin C, in conjunction with iron in the blood, turns into hydrogen peroxide, which in turn produces oxygen. Because the cancer cells can exist only in an anaerobic environment (deprived of oxygen), the oxygen produced is toxic to these cells, causing them to die. To all the healthy cells, the oxygen produced is harmless. Liposomal and intravenous vitamin C in SLE Lupus You'll find a report on the Testimonials page in which a patient with SLE (Lupus) explains how she treated herself successfully with liposomal and intravenous vitamin C. Is to be noted that it is likely a virus (EBV) that caused the disease and eventually succumbed to the vitamin. This report also shows that vitamin C can successfully fight poisoning, regardless if it was caused by drugs or by bacteria. Nowadays, liposomal vitamin C achieves a saturation in the blood that formerly seemed possible only with intravenous administration. However, the latter has its drawbacks.
With every infusion there is the risk of infection. Furthermore, it is not easy and possible for anyone to undergo such a procedure. In addition, an appropriate physician or therapist has to be found willing to administer an infusion. In case a patient does not want to go to all the trouble, liposomal vitamin C is a viable alternative. It can easily be taken at home or at work, thus ensuring the necessary saturation in the blood, which could never be achieved with conventional doses (tablets, capsules or liquids). The liposome produced with nanotechnology, which we have on offer is very well absorbed by the body, since the lipid used has the same structure as the cell walls. This image sequence illustrates the life of a liposome from its creation to its fulfillment of purpose. Click on the image to start. Dosage of liposomal vitamin C 1 - 2 g according to severity: 3 - 6 g according to severity and jeopardy: 6 - 12 g (Warning: heavy metal intoxications: Jarisch-Herxheimer reaction)