In their book You: Being Beautiful - The Owner's Manual to Inner and Outer Beauty (Free Press, 2008) co-authors Mehmet Oz, MD and Michael Roizen, MD refer to ribose as one of the decade's "real nutritional heroes" that can turbo-charge those who need an energy boost. D-Ribose is a naturally occurring simple sugar found in all living cells. It is the fuel that mitochondria use to produce adenosine tri-phosphate (ATP), which provides the body’s cellular energy. Studies show that patients with fibromyalgia, chronic fatigue syndrome (CFS) and congestive heart failure are low in D-Ribose. Fibromyalgia and chronic fatigue syndrome affect twice as many women as men and typically first appears at middle age. It still isn’t clear what the cause is but studies indicate that people with fibromyalgia have lower levels of ATP and a reduced capacity to make ATP in their muscles. Recent studies show that ribose supplementation can reduce muscle pain and enhance quality of life for those suffering with fibromyalgia and/or chronic fatigue.
According to Tori Hudson, ND, “As cellular energy is depleted, fatigue and muscle pain become more and more severe, and the muscles require additional energy in their recovery efforts. Energy is used faster than fuel is made available to renew it, and the fatigue, soreness, pain and stiffness continue to progress. Energy depletion reaches a critical point, and CFS/FMS becomes a state in which the mechanisms for recovery are overwhelmed.” A 2006 study published by Jacob Teitelbaum, MD in the Journal of Alternative and Complementary Medicine showed that D-Ribose significantly reduced clinical symptoms in patients suffering from fibromyalgia and chronic fatigue syndrome. Forty-one patients with a diagnosis of fibromyalgia and/or CFS were given D-Ribose, at a dose of five grams a day, three times a day. The study found that two-thirds of the patients reported improvement of their symptoms in the first 12 days following a course of D-Ribose treatment. The average improvement in energy was 45% and quality of life improved an average of 30%.
Patients reported less muscle soreness and stiffness, better ability to overcome fatigue, as well as simply feeling better. Patients reported less muscle soreness and stiffness, better ability to overcome fatigue, as well as simply feeling better.3 Recommended dose for fibromyalgia and CFS is five grams, three times a day. Look for a brand that is pure D-Ribose, and remember you need to take it for an average of 12 days to start feeling better. Congestive heart failure (CHF), or heart failure, is a condition in which the heart can't pump enough blood to the body's other organs. Millions of Americans suffer from CHF, and more than 500,000 cases are diagnosed annually. People with heart failure can't exert themselves because they become short of breath and extremely tired. Although most people with mild and moderate CHF can be treated with drugs, most patients show progression of their disease. Numerous studies have shown that the failing heart is energy starved and that D-Ribose can replenish ATP levels and improve diastolic dysfunction following heart failure.4
A recent study showed that patients who took five grams of ribose three times a day for eight weeks showed significant improvement.5 Doctors Stephen Sinatra and James Roberts recommend the following dosages in their book Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It’s Too Late6: • Start at the upper level of each range for patients with heart or peripheral vascular disease. We recommend that daily doses up to 10 grams be taken as two 5-gram doses with morning and evening meals or just before and just after exercise or activity. Larger doses (15 grams per day or more) should be taken in three or sometimes even four smaller doses of about 5 grams each. Daily doses in excess of 30 grams are seldom needed. Most heart patients will stabilize at about 10 grams per day.6 The natural health solutions described in this article are available through many on-line retailers including those listed below. By clicking these links you help support the important alternative health research we provide.
Visit NutriStand – The Nutrition Newsstand from the Supplement Man for Science-Based Nutritional Supplements! Visit International Antiaging-Systems for hard to find therapies. They specialize in Tomorrow's Treatments Today™. – a great way to find competitive deals on supplements offered by many different manufacturers. Visit VitaE8 - The Ultimate Vitamin E – to learn more about the importance of full-spectrum vitamin E supplements. This article is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a physician before embarking on a dietary supplement program. Oz, M, MD & Roizen, M, MD, Authors of You: Being Beautiful, “Call Ribose One of the Decade's 'Real Nutritional Heroes'." Hudson, T. "D-Ribose, chronic fatigue syndrome, and fibromyalgia. Teitelbaum JE, Johnson C, St Cyr J. The use of D-Ribose in chronic fatigue syndrome and fibromyalgia: a pilot study. J Altern Complement Med. 2006 Nov;12(9):857-62. Wagner S, Herrick J, Shecterle LM, St Cyr JA.
D-Ribose, a metabolic substrate for congestive heart failure. MacCarter D, Vijay N, Washam M, Shecterle L, Sierminski H, St Cyr JA. D-Ribose aids advanced ischemic heart failure patients. Epub 2008 Jul 31. Sinatra, S, MD & Roberts, JC, MD, Reverse Heart Disease (John Wiley & Sons, Inc., Hoboken, New Jersey, 2007) Commenting is not available in this channel entry.Like what you’re reading? Get FREE updates sent to your inbox.Email* I want to improve my...I want to improve my...WeightEnergyDigestionBrainOverall HealthAll of the AboveI hate spam too. Your email is safe with me.Sign into your account to have access to your paid resourceslisted in , originally published in issue 107 - January 2005 I have had CFS for more than ten years, and during the past three years I have been too ill to work. However, I am now at the stage of recovery where I am looking at getting back to work. I refer to CFS as an umbrella term covering many debilitating symptoms. My symptoms, listed as follows, gradually worsened over the years to the point that I was barely able to function:
I was continually exhausted to the point that I was in bed up to 18 hours a day. Some days just walking to the shops around the corner from where I live would render me incapable of doing anything else for the day. I just about managed to make sure I ate regularly and had food in the house. Even any mental activity was exhausting, like watching television, reading, even having a conversation. I was also very sensitive to noise and to a lesser extent light, so on the rare occasion when I visited people I always had to explain that I needed a quiet environment. I suffered from migraine on average once a week and, in between, my head was in constant pain, as once I got over one migraine another would start. I was referred to a neurologist for treatment but none of the medications worked. I also had severe digestive problems with the result that I wasn't absorbing much of my food. My GP put that down to irritable bowel syndrome, and gave me some beta blockers which helped slightly, but not really enough to relieve the problem.
I also had fybromyalgia and joint pains. I had lost a lot of weight which fluctuated between 105 lbs and 112 lbs and I am 5.6 ft in height so I was severely underweight. And no matter how much I ate I was not able to regain my weight. And not surprisingly I was also depressed, although I did make a choice to do everything possible to maintain a positive outlook (more on that later). At this stage I still had some good days, and I decided to devote myself to getting the help I needed. I wasn't able to get much help from the medical profession so investigated, in more depth, complementary therapies which I had used for many years in order to keep myself going. Here are the key interventions which made a big difference: Under the guidance of a nutritionist I changed my diet to include eating meat, particularly chicken and fish, and on occasions red meat. My diet previously was mainly vegetarian which I don't think suited me, as I had a great deal of difficulty digesting pulses and dairy produce, which left me deficient in many nutrients.
And I loosely followed the blood type diet. These changes made a huge difference and I started to build up my body and put on some weight. Because I also had osteoporosis I increased my intake of calcium and magnesium and I started by taking two grams of calcium orotate and magnesium orotate per day, which made a big difference to the chronic head pain and the general muscle soreness within a few weeks. The other key thing was my teeth. I underwent treatment with Mr Amir, a Holistic Dentist with a practice in London. He works with many CFS patients. I found that his treatment improved the symmetry and balance of my jaw, relieved the irritable bowel and migraine symptoms quite dramatically as well as improved my posture and helped build overall confidence. Due to an accident when I was young my jaw was severely out of alignment. I also had quite a lot of decay in my old mercury fillings, which had to be removed and replaced with porcelain fillings. As a result there was a significant improvement in my general health.
It also improved the balance of my face which I was very pleased with. By this stage I was putting on weight, I was able to eat better and digest my food more. My quality of life had certainly improved, which included a better social life. However, even though I was getting far fewer migraines, they were still there. I still had the muscle and joint pain and I felt as if I was constantly walking around with flu, and the exhaustion had not completely lifted. I was finally recommended to see Dr Julian Kenyon at the Dove Clinic who trained as a doctor in conventional medicine which he combines with a complementary approach, and he understood CFS, an area he has done much research. He did a thorough diagnosis and found that I had a high chronic high viral load in my system which was probably the main cause of my illness. This is the first time that a cause for my illness was identified. He also identified a depleted immune system, with a resulting toxic overload in my body. This diagnosis also restored my sense of reality – I was ill and that was now objectively confirmed and we could do something about it.
Dr Kenyon has worked on giving me supplements and nutritional support to build up a depleted immune system and, because my viral load was quite high, I had intravenous Vitamin C and glutathione to detoxify my body and get rid of the virus. I am awaiting the results of the treatment, but I feel so much better and am now looking at getting back to work. I feel for me all of the above interventions were necessary in my journey from where I was three years ago to where I am now. I have also needed to change my outlook on life. Even though I was always a fairly positive person I really concentrated on maintaining a positive attitude. I have also felt the need to give space to the not so good days and really engage with those negative and depressing thoughts and feelings, listen to what they have to say but then move on. CFS has taught me a lot of patience, about taking things a step at a time and really dwelling on the small victories. I no longer take anything for granted and I am so grateful for each small step in my recovery.