SureSwab® - Bacterial Vaginosis and Vaginitis Test Why test for everything, when you can simply test for the right thing? Quest Diagnostics offers organism-specific molecular tests available individually or in panels. Because of the close association between STIs and bacterial vaginosis and Candida infection, the SureSwab® Vaginosis/Vaginitis Plus panel includes tests for C. trachomatis, N. gonorrhoeae, and T. vaginalis as well as tests for bacterial vaginosis and Candida spp. SureSwab®… a difference in BVV testing An accurate diagnosis of Bacterial Vaginosis and Vaginitis (BVV) depends on more than identifying the presence of organisms. Vaginosis occurs when the balance of the bacterial flora in the vaginal ecosystem is disrupted.[[1 - 5] SureSwab is a molecular, quantitative test for vaginosis with results that support a more definitive diagnosis. SureSwab provides a clear indication as to whether or not an imbalance exists versus conventional qualitative approaches that test for a broad array of organisms.
Targeted Testing Is the Most Clinically Appropriate Choice for Women with[6]: Symptoms of Vaginitis History of high-risk sexual behavior or a previous STI History of pregnancy complications (e.g. ectopic pregnancy, premature rupture of the membranes preterm labor and delivery) Cervictis, pelvic inflammatory disease, urethritis Chronic pelvic pain, difficult urination, painful intercourse Risk of post-operative gynecologic infection Online Resources for Healthcare Professionals Visit our Test Selection and Interpretation Guide for information relating to test selection, utilization and interpretation. Obtain test ordering codes and specimen requirements from our online Test Menu Simplify test ordering and reporting with our connectivity solutions Contact a Quest Diagnostics Sales Representative, learn more about our testing services, and become a client Contact a physician sales representative Contact a hospital sales representative or learn about our complete hospital offerings References Egan M and Lipsky M. Diagnosis of Vaginitis.
Am Fam Physician 200;621095-1104 Fredricks DN Fiedler TL, Marrazzo JM Molecular identification of bacterial associated with bacterial vaginosis, N Engl J Med. 2005;353:1899-1911 Menard JP,Fenollar F. Henry M. Et al. Molecular quantification of Gardnerella vaginalis and Atopobium vaginae loads to predict bacterial vaginosis. Clin Infect Dis.2008;47:33-43 Ferris M. et al. Association of Atopobium vaginae, a recently described metronidazole resistant anaerobe, with bacterial vaginosis. BMC Infectious Diseases 2004;4-5 Zozaya-Hinchliffe M. Martin DH, Ferris MJ. Prevalence and abundance of uncultivated Megasphera-like bacteria in the human vaginal environment. 2008;74;1656-1659 Centers for Disease Control and Prevention, Workowski KA. Berman SM. Sexually transmitted diseases treatment guidelines 2006. MMWR Recomm Rep. 2006;55(RR-11);1-94 Erratum in:MMWR Recomm Rep. 2006;56-997.Digital Mammo: Better Ca Detection, But Also More BiopsiesMore HPV Pathology with Single-Dose VaccineFew Teens Treated Well for Opioid AddictionDoctors Mixed on Housecall AppsPodMed: A Medical News Roundup From Johns Hopkins
Low Vitamin D Could Make for Tough Pregnancy Pregnant women with insufficient levels of vitamin D may be at increased risk of gestational diabetes, preeclampsia, and having infants small for their gestational age, a new meta-analysis showed. They also may have an increased chance of bacterial vaginosis and lower-birth-weight infants, according to Doreen Rabi, MD, of the University of Calgary in Canada, and colleagues. On the other hand, they were not more likely to deliver by cesarean section, Rabi and colleagues reported online in BMJ. Low levels of 25-hydroxyvitamin D (25-OHD) have been associated with adverse health outcomes, including those in pregnancy, the researchers noted, but understanding of the clinical implications is limited. However, published research on vitamin D insufficiency in pregnancy has been "growing rapidly," requiring systematic review and meta-analysis to clarify its clinical importance. They found 31 studies reporting on links between serum 25-OHD levels during pregnancy and pregnancy outcomes (defined as preeclampsia, gestational diabetes, bacterial vaginosis, and C-section) and birth variables (small for gestational age, birth weight, birth length, and head circumference).
Ten studies reported on gestational diabetes, 10 reported on birth variable, nine on preeclampsia, three on bacterial vaginosis, and two on C-section. One study had data on two of the outcomes of interest. All the studies -- with between 95 and 1,100 participants -- were published between 1980 and 2012. Fifteen were case-control studies, 11 were cohort studies, and five had other designs, but all used a comparison group. For the analysis of pregnancy outcomes, Rabi and colleagues defined vitamin D insufficiency to be a serum 25-OHD concentration of less than 75 nmol/L, while for birth variables, they defined it as less than 37.5 nmol/L. The analyses showed that insufficient vitamin 25-OHD was associated with: Gestational diabetes: pooled odds ratio 1.49 (95% CI 1.18 to 1.89) Preeclampsia: pooled OR 1.79 (95% CI 1.25 to 2.58) Having an infant who was small for gestational age: pooled OR 1.85 (95% CI 1.52 to 2.26) Three studies looked at bacterial vaginosis and all found an increased risk for women with low 25-OHD, but differences in statistical reporting meant a meta-analysis couldn't be performed, Rabi and colleagues explained.
The four studies that reported on birth weight found that infants of mothers with low 25-OHD concentrations averaged 130 g lighter (random weighted mean difference −130.92 g, 95% CI −186.69 to −75.14 g) than those of mothers in the normal range, but birth length and head circumference did not differ significantly. Of the two studies that looked at the risk of C-section, one found an increased risk for mothers with low 25-OHD and one did not. Overall, the findings "support a goal of vitamin D sufficiency for all pregnant women," commented Robyn Lucas, MBChB, PhD, of the Australian National University in Canberra, and colleagues. In some parts of the world – notably Asia and Africa – reaching such a goal might lead to important gains in health, if there are causal links between vitamin D deficiency and adverse maternal and neonatal outcomes, they commented in an accompanying editorial. But current evidence poses challenges because it's derived mainly from observational studies and small trials, they cautioned.