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Studies that didn’t find a connection in animals
A meta-analytic review published in 2013 reviewed 10 previous rodent studies on aspartame and cancer risk conducted before December 31, 2012. The review of the data found that aspartame consumption has no carcinogenic effect in rodents.
Studies that didn’t find a connection in humans
One of the largest studies on the possible link between aspartame and cancer was performed by researchers from NCI. They reviewed 285,079 men and 188,905 women ages 50 to 71 who participated in the NIH-AARP Diet and Health Study.
The researchers concluded that aspartame wasn’t associated with the development of brain cancer, leukemia, or lymphoma.
A 2013 review of evidence of other studies on aspartame consumption and various cancers also found no association between aspartame and cancer risk.
A systematic review of the link between artificial sweeteners and cancer in humans was conducted using data from 599,741 people from 2003 to 2014. It was concluded that the data didn’t provide conclusive evidence linking aspartame to cancer.