Закладки MDMA в Чермозе

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Экстази и MDMA: все о эффектах и последствиях

Закладки MDMA в Чермозе

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While this is a fantastic piece of news for PTSD sufferers and proponents of drug-policy reform, it might not make much difference to the average person. The MDMA-assisted psychotherapy being trialed by the Multidisciplinary Association for Psychedelic Studies would only become available to a select few — most likely those who could afford the treatment, or had serious medical reasons for needing it. Unsurprisingly, the public will still want to get its share of the life-enhancing benefits being touted by researchers and therapists. Everyone from entrepreneurs to artists are microdosing psychedelics like LSD, psilocybin, and mescaline for spiritual, creative, and productive enhancement. I do it about once a week, sometimes a bit more, every four to five days. I take very, very tiny eyeballed doses, maybe milligrams, if I were to guess. The come down left me in my bed for weeks. I refused to see people, shut my phone off, and genuinely hid from the outside world. The Tab. One well-known study looked at 29 recreational users of ecstasy, who typically took high doses more than twice a week. None of the control subjects had any similar defects. High concentrations of the 5HT2B receptor are found on the heart — and when these are activated by MDMA, it sets in motion a signaling pathway that can cause defects in the heart valves if kept active for too long. MDMA is one of the strongest activators of the 5HT2B receptor, so it could still be having a significant effect at low doses. Perhaps a therapeutic dose, in a comfortable surrounding and with appropriate support, is still the safest and most effective way of benefitting from ecstasy. Microdosing stimulants can make you over sensitive to it. To the point where eating your dinner normally at night even gives you a rush. Another main issue is if you microdose mdma for a while then take a normal dose, might you overdose? Wonder if this guy knows anything? Hello Everyone. So people literally thought I was myself.. This lead to me starting to crush them up and sniff them….. I am still consuming it this way to this day. They are NOT the same thing. I believe MDMA is great for PTSD and that is an issue people have to work on in the short term, not something to avoid the symptoms of by taking microdoses. Every substance should be a medicine used to overcome the illness and then stop taking it. MDMA os a stimulant but that is not what you should look for, i believe. Which is why it is tested on a normal dose with psychotherapy. Personally I am using it for meditating on fearful trauma, following the 3 cycle 1 dose before, half dose afterwards. The stimulant effect is minimum and affects only my brain, not the body. But like LSD it keeps me awake so would never think of microdosing. Besides, because its great effect on those who struggle with anxiety, I think it could give mental addiction. I find it odd that this person experienced any negative comedown from taking pure MDMA. In my experience that only occurs when it is adulterated, probably with speed. As for it being bad for the heart, I have taken it many times and several doctors have told me I have the healthiest heart they have ever seen for someone like me, who was born with congenital heart disease. Omg yes, I was born with nitro valve prolapse and after 4 hard years of taking mg in a 5 day period of time, my heart is in excellent health. Think for yourself. Extremely thin argumentation in this post. No , they are activated by Serotonin. Heard of that? The stuff already present in your blood? It should be obvious that a only small increase of Serotonin as caused by microdosing does not have the same effect on the heart and probably none at all. Otherwise merely having a good day with lots of fun which comes with a similar increase of Serotonin would be deadly as well. You just claim that daily use of MDMA is risky. But this is to circumstances like serotonin depletion. Again it should be obvious that serotonine depletion does not happen with microdosing. Really, how can you totally ignore the correlation between dosing and serotonine release and treat it like every dose does the same? But your article really does not help at all and feels little more than just fearmongering with thin and borderline invalid arguments. Therefore even small doses of MDMA are probably affecting serotonin signaling in a manner that is incomparable to other boosts of serotonin, such as lifestyle factors that affect serotonin levels. It is also not possible to rule out the fact that serotonin depletion could be a factor in chronic microdosing. I take a firm stance on this. Our article is not fearmongering. It would be deeply wrong for us to not report on this. If I started to feel any discernible effects, I would back it down from wherever that was. The reason I bring up dosages, as with most drugs, outcomes are very dose-specific. It is also not recommended that people with heart conditions take Adderall, as with any amphetamines. Whether or not it is a good idea that we give kids amphetamines so they can pay attention to lectures for 8 hours a day is a whole other can of worms, but it is clear that most people can live relatively healthy lives while taking daily doses of amphetamines, if done in proper dosage ranges. Would there be any potential benefits? The last paragraph in your reply to Sarah is wrong. You may have looked at evidence, however you fail to clearly demonstrate that the research you looked at is relevant to your claim—thus you are not entitled to claim with any certainty that micro-dosing MDMA is dangerous for the reasons you provide. This kind of rumor pedaling is what lead a generation of people to believe that acid flashbacks were a thing, crack is x more dangerous than cocaine and that both are physiologically addictive , prescribed opioids are safe and non-addictive but heroin is death, etc. Know that without editing this article significantly, you are contributing to the misinformation echo-chamber that prevents people from objectively considering the potential benefits of all drugs while considering the downsides in a measured and educated fashion. Hi Sid. Thanks for your concern on this topic. We appreciate people guarding against scaremongering and keeping the psychedelic community aware of the dangers of false information. We make it clear that the studies performed on MDMA are on high doses. We make it clear that there is no solid evidence that microdosing MDMA would be toxic. But we highlight the need for caution and the fact that the science points towards MDMA being a potentially harmful substance. I do not believe this is fearmongering. Our stance here is based on solid research and caution, rather than irrational fear and prejudice. I believe we have not misrepresented any of the research, or misled anyone. This is a harm-reduction article designed to protect people from undertaking a potentially risky activity. I believe this article presents the evidence in a way that lets people make up their own mind based on the incomplete knowledge that we possess. We are providing solid evidence that MDMA can be toxic, and it would be reasonable to avoid microdosing until more is known. I stand by the way this article is presented and the reasoning within it. Please do keep interacting with us. This kind of discussion is crucial to make sure the community is going in the right direction. Choosing to not modify the article to be more clear and specific, and evidence-based is dangerous. Spreading misinformation like this is dangerous. Your stance is based on what amounts to biased studies, and not even many of them. This is not harm-reduction, it is fear mongering. My heart always feels a bit off when taking ecstasy pill, but not when taking pure MDMA crystals. The solution: oxitocin — walk around asking to hug people, and do so legitimately and deliberately. Then tell me how 5HT2B receptors are doing. I was micro-dosing MDMA for one and half weeks when my office work pilled up. I was really active during those days and my work efficiency doubled. I was able to complete my work in a weeks time. But, unlike other psychedelics MDMa was more addictive. I planned to microdose for a week but i continued the same for the next few weeks. Moreover unlike LSD or shrooms, each day i have to increase the dose to get the same level of high as previous day. Your email address will not be published. Save my name, email, and website in this browser for the next time I comment. Share Tweet Share. More posts like this one. Comments Microdosing stimulants can make you over sensitive to it. I left the MDMA for about 2 weeks.. Haha You are prety misinformed about the purity vs comedown. You have a cogenital heart disease! That calms the heart completely. Leave a Reply Cancel reply Your email address will not be published.