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Subject: 1 selected item: 12496826 - PubMed
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Affiliation
1 Institute for Male Urology, Encino CA and the Division of Urology, Harbor-UCLA Medical Centre, Torrance, CA.
D A ShoskesΒ et al. Prostate Cancer Prostatic Dis. 1999 May.
Affiliation
1 Institute for Male Urology, Encino CA and the Division of Urology, Harbor-UCLA Medical Centre, Torrance, CA.
Chronic prostatitis is often refractory to antibiotics, however biopsy and molecular data indicate persistent symptoms may be due to occult infection. Combining antibiotic therapy with regular prostatic massage has been suggested as an effective therapy for some of these men. From November 1996 to December 1998, 73 men with chronic pelvic pain syndromes were treated with antibiotics and prostatic massage. Antibiotic selection was based on culture and sensitivity of prostatic fluid or empirically if cultures were negative. Prostatic massage was done 1 to 3 times per week and fluid examined for WBCs and cultured for bacteria. The average age of the group was 43.5 y (range 23-72) and average duration of symptoms 6.7 y (median 3 y, range 3 months-30 y). Prostatic cultures were negative in 19, grew uropathogens in 2, and Gram positive bacteria in 52 patients. Overall 29 patients (40%) had complete resolution of symptoms, 14 (19%) had complete resolution followed by a recurrence, 15 (21%) had some improvement and 15 (21%) had no improvement. All positive cultures were sterilized during treatment. Combination prostatic massage and culture specific antibiotics can be an effective treatment in a proportion of men with long standing refractory chronic prostatitis.
Ateya A, Fayez A, Hani R, Zohdy W, Gabbar MA, Shamloul R. Ateya A, et al. Urology. 2006 Apr;67(4):674-8. doi: 10.1016/j.urology.2005.10.021. Epub 2006 Mar 29. Urology. 2006. PMID: 16566972 Clinical Trial.
Nickel JC, Shoskes D, Wang Y, Alexander RB, Fowler JE Jr, Zeitlin S, O'Leary MP, Pontari MA, Schaeffer AJ, Landis JR, Nyberg L, Kusek JW, Propert KJ. Nickel JC, et al. J Urol. 2006 Jul;176(1):119-24. doi: 10.1016/S0022-5347(06)00498-8. J Urol. 2006. PMID: 16753385
Nickel JC, Downey J, Feliciano AE Jr, Hennenfent B. Nickel JC, et al. Tech Urol. 1999 Sep;5(3):146-51. Tech Urol. 1999. PMID: 10527258
Naber KG. Naber KG. BJU Int. 2008 Mar;101 Suppl 3:7-10. doi: 10.1111/j.1464-410X.2008.07495.x. BJU Int. 2008. PMID: 18307679 Review.
Nickel JC, Alexander R, Anderson R, Krieger J, Moon T, Neal D, Schaeffer A, Shoskes D. Nickel JC, et al. Tech Urol. 1999 Mar;5(1):1-7. Tech Urol. 1999. PMID: 10374787 Review.
Phua TJ. Phua TJ. Medicines (Basel). 2021 Jun 11;8(6):30. doi: 10.3390/medicines8060030. Medicines (Basel). 2021. PMID: 34208086 Free PMC article. Review.
Vaidyanathan R, Mishra VC. Vaidyanathan R, et al. Indian J Urol. 2008 Jan;24(1):22-7. doi: 10.4103/0970-1591.38598. Indian J Urol. 2008. PMID: 19468353 Free PMC article.
Dhar NB, Shoskes DA. Dhar NB, et al. Curr Urol Rep. 2007 Jul;8(4):313-8. doi: 10.1007/s11934-007-0078-5. Curr Urol Rep. 2007. PMID: 18519016 Review.
Duclos AJ, Lee CT, Shoskes DA. Duclos AJ, et al. Ther Clin Risk Manag. 2007 Aug;3(4):507-12. Ther Clin Risk Manag. 2007. PMID: 18472971 Free PMC article.
Shoskes DA, Katz E. Shoskes DA, et al. Curr Urol Rep. 2005 Jul;6(4):296-9. doi: 10.1007/s11934-005-0027-0. Curr Urol Rep. 2005. PMID: 15978233 Review.
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Subject: 1 selected item: 16360449 - PubMed
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Affiliation
1 Urology Clinic, Kartal Training and Research Hospital, Istanbul, Turkey. tarhanf@yahoo.com
Fatih TarhanΒ et al. Urology. 2005 Dec.
Affiliation
1 Urology Clinic, Kartal Training and Research Hospital, Istanbul, Turkey. tarhanf@yahoo.com
Objectives: To evaluate the effects of prostatic massage on the serum complexed PSA (cPSA) concentration in various prostatic diseases.
Methods: A total of 51 men who presented to our outpatient clinic for the first time with symptoms of lower urinary outflow obstruction were included in this study. Blood samples were obtained from each patient before and 30 minutes after prostatic massage. Total PSA (tPSA), free PSA (fPSA), and cPSA levels were measured using a chemiluminescent enzyme immunoassay.
Results: After prostatic massage, the tPSA and fPSA levels and fPSA/tPSA ratio increased significantly (P < 0.0001), and the increase in cPSA was minimal but statistically significant (P = 0.047). In patients with prostate cancer, no significant increase occurred in the mean forms of PSA (tPSA, cPSA, and fPSA/tPSA ratio), except for fPSA, after prostatic massage. We observed a greater increase in all PSA forms in the chronic prostatitis group.
Conclusions: In this study, prostatic massage increased serum cPSA concentration, but to a lesser extent than tPSA and fPSA.
Filella X, Truan D, Alcover J, QuintΓ³ L, Molina R, Luque P, Coca F, Ballesta AM. Filella X, et al. Urology. 2004 Jun;63(6):1100-3; discussion 1103-4. doi: 10.1016/j.urology.2004.01.056. Urology. 2004. PMID: 15183958 Clinical Trial.
Mazo EB, Sergeeva NA, Grigor'ev ME, Lebedev DV, Solov'eva EV, Konorev VA, Krovets AA. Mazo EB, et al. Urologiia. 2006 May-Jun;(3):21-4. Urologiia. 2006. PMID: 16889084 Russian.
Li Y, Xu P, Zhang PA, Su HW, Zhang J. Li Y, et al. Zhonghua Nan Ke Xue. 2003 Aug;9(5):361-3, 366. Zhonghua Nan Ke Xue. 2003. PMID: 14513646 Chinese.
Jansen FH, Roobol M, Jenster G, SchrΓΆder FH, Bangma CH. Jansen FH, et al. Eur Urol. 2009 Mar;55(3):563-74. doi: 10.1016/j.eururo.2008.11.040. Epub 2008 Nov 29. Eur Urol. 2009. PMID: 19058905 Review.
Mazzucchelli R, Colanzi P, Pomante R, Muzzonigro G, Montironi R. Mazzucchelli R, et al. Adv Clin Path. 2000 Jul;4(3):111-20. Adv Clin Path. 2000. PMID: 11080790 Review.
Ding T, Zhu Y, Jin H, Zhang P, Guo J, Zheng J. Ding T, et al. Front Cell Dev Biol. 2021 Feb 26;9:644397. doi: 10.3389/fcell.2021.644397. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33718387 Free PMC article.
Gong H, Chen X, Jin Y, Lu J, Cai Y, Wei O, Zhao J, Zhang W, Wen X, Wang Y, Chen W. Gong H, et al. Int J Clin Exp Pathol. 2019 Oct 1;12(10):3839-3846. eCollection 2019. Int J Clin Exp Pathol. 2019. PMID: 31933772 Free PMC article.
Schlauch KA, Read RW, Lombardi VC, Elhanan G, Metcalf WJ, Slonim AD; 23andMe Research Team, Grzymski JJ. Schlauch KA, et al. G3 (Bethesda). 2020 Feb 6;10(2):645-664. doi: 10.1534/g3.119.400910. G3 (Bethesda). 2020. PMID: 31888951 Free PMC article.
Pan Y, Zhang R, Chen H, Chen W, Wu K, Lv J. Pan Y, et al. Med Sci Monit. 2019 Jan 4;25:98-106. doi: 10.12659/MSM.911818. Med Sci Monit. 2019. PMID: 30608062 Free PMC article.
Lieberman HB, Rai AJ, Friedman RA, Hopkins KM, Broustas CG. Lieberman HB, et al. Transl Cancer Res. 2018 Jul;7(Suppl 6):S651-S661. doi: 10.21037/tcr.2018.01.21. Epub 2018 Jan 14. Transl Cancer Res. 2018. PMID: 30079300 Free PMC article.

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