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Follow Erowid on Instagram! Caution : Dose information should not be taken as recommendations. Methamphetamine is usually found in the underground markets as powder or crystals. Street meth, like many other street drugs, is often cut or is not meth at all. Street meth dosages vary by how pure the material is, by individual tolerance based on past usage, how frequently it is used, and by differences in individual reaction. Dosages given below are based on pure meth for an infrequent user. Dosages of mg per day are common for prescription pharmaceutical methamphetamine taken orally, usually spread out into two doses. A common although unhealthy use pattern for methamphetamine is to redose repeatedly for several days in a row. Redosing often involves taking the same dose as the initial dose. As redosing continues beyond 48 hours, the dosages tend to go up. These heavy users may go through a gram or more per day. The euphoric feeling associated with strong doses of meth fades quickly and after several doses in a row or using meth on multiple days in a row, much higher doses are necessary to achieve a similar level of feeling happy and upbeat. MAO inhibitors and CYPD6 inhibitors can increase the effects of methamphetamine and can dangerously inhibit the metabolism of all amphetamines. Some prescription pharmaceuticals are known for producing this effect and new users or users combining herbs, smart drugs, prescriptions, or psychoactive chemicals should be extremely careful of possible interactions. Every individual reacts differently to every chemical. This information is intended to describe the range of dosages people report using. It should not be construed as a recommendation of any sort. Individuals can respond very differently to the same dosage. What is safe for one can be deadly for another. Permission required before publicly reproducing Erowid info. Oral Methamphetamine Dosages. Note: doses for street meth or frequent use may be higher see above. Onset : 20 - 70 minutes depending on form and stomach contents Duration : 3 - 5 hours Coming Down : 2 - 6 hours Normal After Effects : up to 24 hours. Insufflated Snorted Methamphetamine Dosages. Injected IV Methamphetamine Dosages. Note: doses for street meth or frequent use are generally higher see above. Created by Erowid - Unknown.