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Mephedrone belongs to a group known as the substituted cathinone, which are derivatives of the active ingredient in the khat plant Catha edulluis. Email me when this product back in stock. Fill in the form below to be notified when the product back in stock Mephedrone was first synthesized in , but did not become widely known until it was rediscovered in By , it was reported to be available for sale on the internet, by law enforcement agencies had become aware of the compound, and by it had been reported in most of Europe, becoming particularly prevalent in the United Kingdom. It comes in the form of tablets or a powder, which users can swallow, snort, inject or insert rectally, producing effects which are somewhat similar to those of MDMA, amphetamine, and cocaine. It is reported to produce a mixture of classic stimulant and entactogenic effects effects reminiscent of cocaine and MDMA. Mephedrone, or 4-methylmethcathinone, is a synthetic molecule of the cathinone family. Amphetamines and cathinones are alpha-methylated phenethylamines, cathinones contain an additional carbonyl group at R1. Given its chemical structure, mephedrone is likely to act as a releasing agent and a reuptake inhibitor for monoamine neurotransmitters such as dopamine, serotonin and noradrenaline. Several articles published near the end of examined the effects of mephedrone in the brains of rats, as well as examining the reinforcing potential of mephedrone. Dopamine and serotonin were collected using microdialysis, and increases in dopamine and serotonin were measured. They reached their peak concentrations at 40 minutes and 20 minutes and returned to baseline by minutes after injection. Analysis of the ratio for dopamine and serotonin indicated mephedrone was preferentially a serotonin releaser, with a ratio of 1. Additionally, half-lives for the decrease in dopamine and serotonin were calculated and found to have decay rates of These findings show mephedrone induces a massive increase in both dopamine and serotonin, combined with rapid clearance. This increase in neurotransmitters provides an explanation for the euphoric and stimulating subjective effects induced by this experience. The rapid rise and subsequent fall of dopamine levels could also explain some of the addictive properties of mephedrone display in some users. Mephedrone , also known as 4-methyl methcathinone 4MMC or 4-methyl ephedrone, is a synthetic stimulant drug of the amphetamine and cathinone classes. It is chemically similar to the cathinone compounds found in the khat plant of eastern Africa. It comes in the form of tablets or a powder, which users can swallow, snort or inject, producing similar effects to MDMA, amphetamines and cocaine. In addition to its stimulant effects, mephedrone produces side effects, of which teeth grinding is the most common. The metabolism of Mephedrone has been studied in rats and humans and the metabolites can be detected in urine after usage. The synthesis of Mephedrone in , but did not become widely known until it was rediscovered in at which point it was legal to produce and possess in many countries. By , mephedrone was reported to be available for sale on the Internet, by law enforcement agencies had become aware of the compound, and by , it had been reported in most of Europe, becoming particularly prevalent in the United Kingdom. This may be true, but it may also be due to transfigured memories, receptors destroyed by excessive consumption, or tolerance development. The effect of mephedrone may be considered to be comparable to cocaine, but it is more empathogenic than egopushing. The euphoric effect is usually much more noticeable than the stimulating one, the more it is refilled, the weaker is the euphoria. There are many different substances that are being marketed as mephedrone substitutes, many consumers are looking for a similarly intensive stimulant and are ready to take many, sometimes very unknown, cathinones. The most popular substitute is 3-MMC, which has also been illegalized in most countries including Germany. Solubility data refer to Mephedrone HCl. Other names: mephedrone, mephedrone, 4-MMC, 4-methylmethcathinone, 4-methylmethcathinone, 4-methyl-ephedron, 4-methyl-ephedrone, 4-methylephedrone, 4-methylephedrone engl. There is not enough information about this substance! Hardly any reports from consumers and certainly very few scientific papers. Accordingly, the consumption is an unpredictable risk, possible toxic effects may be undetected. We strongly advise against taking it! The following information is a collection of information taken from reports about this designer drug. We can not guarantee the accuracy and recommend to anyone to consult further sources. The effects and side effects listed here are all very subjective and are perceived differently by each person. They do not always have to occur and there may be other, unmentioned effects. Then we would be pleased about a comment on this! These lists should not serve as a guarantee, but as a guide. Empathic — 4-MMC can increase empathy for other people. Mephedrone 4 MMC is an Upper that is not overly stimulating, but very euphoric and empathogenic sometimes increasing self-esteem. Since euphoria is a very important component of the effect, the addictive potential is significantly higher than with amphetamine, 2-MMC, 2-FA etc. In general, the effect is Cathinone-typical, people who have never consumed cathinone may imagine it to be similar to cocaine, with MDMA-like effects also present, 4-MMC is considered more empathic than cocaine. The aphrodisiac effect is very strong, the orgasm is intensified. Because of this, sexual intercourse after having experienced sex on mephedrone or other upsets is less fun than before for some consumers, which may also be a reason for addiction. It makes a big difference whether you consume 4-methylmethcathinone orally or nasally. Compared to 3-MMC 3-methylmethcathinone , mephedrone is usually much more euphoric and intense! In addition, the nasal mucosa are severely damaged by the substance, it can cause nosebleeds, etc. If the mephedrone is obtained in crystalline form, it should be comminuted as well as possible because coarse crystals cause fine cuts. Also intravenous, inhalative, rectal and sublingual consumption is possible, but little is known about these forms of consumption. Inhalative use is very dangerous and harmful, the craving is enormous and you have to choose significantly lower dosages, some consumers also report violent palpitations and other side effects. The same applies to intravenous consumption, here comes the serious damage to the veins added. Although rectal use is slightly less harmful than inhaled and intravenous use, it can still damage the intestinal mucosa and produce a tremendously strong effect. These dosage indications are only approximate guidelines derived from consumer reports. It must be started with an allergy test and a very low dose! More Safer Use rules can be found here. Effect on after: minutes Main effect: hours Coming down: minutes Afterglow: hours. How exactly it works in the human brain has not been clarified, but there are some animal studies in rats, which showed that the dopamine and serotonin levels in the brain was increased. The serotonin concentration was increased more than the dopamine concentration at a rate of 1. Every single combination has to be informed in advance and experience reports must be searched for as there can always be dangerous interactions. Other stimulants: The mixed use of different stimulants is potentially very dangerous as the blood pressure and heart rate are greatly increased and side effects such as dehydration are also increased. Here is the study. The effect can unpredictably potentiate and there can be dangerous interactions such as severe neurotoxicity or a serotonin syndrome , so you have to know exactly about every single combination that you want to take! The mixed consumption of stimulants with this psychedelic is life threatening! Psychedelics: Other psychedelics can also cause complications with blood pressure and circulation when mixed with stimulants. Also, the psychic side is not to be underestimated, since the upper paranoia and increase the risk of a dip trip. Blood pressure and heart rate are increased and also here it can come to mental problems panic attacks, Badtrip. Alcohol: greatly increased dehydration! The effect of the alcohol is suppressed by the Upper, so it can no longer be estimated whether drinking too much. This can lead to alcohol poisoning, which can be life-threatening. As mentioned above, there is a study examining the effect of mephedrone in mixed use with MDMA in rats, where there is an increased neurotoxicity. MAO inhibitor: deadly combination! Heart rate and blood pressure can be increased. In addition, the sedative component of the downer is suppressed, which is why it can easily come to an overdose, because the consumer can no longer estimate how strong the effect of the downer is already and he therefore possibly nachlegen. Mephedrone, also known as 4-methyl methcathinone 4-MMC or 4-methyl ephedrone, is a synthetic stimulant drug of the amphetamine and cathinone classes. Slang names include drone,It is chemically similar to the cathinone compounds found in the khat plant of eastern Africa. The metabolism of mephedrone has been studied in rats and humans and the metabolites can be detected in urine after usage. Wost customers that have ordered from us know more about the product. To buy 4-mmc mephedrone just choose quantity,add to cart and proceed to checkout. Product Weight Choose an option 1g 5g 10g 25g 50g g g g g Clear selection. Add to Wishlist. Remove from Wishlist. Share this. Research Chemicals of mephedrone 4 mmc Mephedrone, or 4-methylmethcathinone, is a synthetic molecule of the cathinone family. Pharmacology of Mephedrone 4MMC. Mephedrone 4mmc Mephedrone , also known as 4-methyl methcathinone 4MMC or 4-methyl ephedrone, is a synthetic stimulant drug of the amphetamine and cathinone classes. More at Wikipedia In addition to its stimulant effects, mephedrone produces side effects, of which teeth grinding is the most common. Buy mephedrone 4MMC Mephedrone 4-MMC for sell The synthesis of Mephedrone in , but did not become widely known until it was rediscovered in at which point it was legal to produce and possess in many countries. Additional Information. Additional information Product Weight 1g, 5g, 10g, 25g, 50g, g, g, g, g. Reviews 0. Reviews There are no reviews yet. Related Products Quick View Select options. Quick View Select options. Марихуана купить Москва Москворечье-Сабурово. 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