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Benzo Fury 6 Apb Купить
It is similar in structure to MDA , but differs in that the 3,4- methylenedioxyphenyl ring system has been replaced with a benzofuran ring. It may appear as a tan grainy powder. While the drug never became particularly popular, it briefly entered the rave and underground clubbing scene in the UK before its sale and import were banned. It falls under the category of research chemicals , sometimes called 'legal highs. The potent agonism of the 5-HT 2B receptor makes it likely that 6-APB would be cardiotoxic with chronic or long-term use, as seen with other 5-HT 2B receptor agonists such as the withdrawn serotonergic anorectic fenfluramine. The pharmacokinetics of 6-APB have not been studied, however, some information can be extracted from user reports. These suggest a slow onset of 40— minutes. The drugs peak effects last 7 hours, followed by a comedown phase of approximately 2 hours, and after effects for up to 24 hours. Although limited literature is available, there is some data on metabolism of 6-APB in rats. Its Phase I metabolism involves hydroxylation of the furan ring, then cleavage of the ring, followed by a reduction of the unsaturated aldehyde from the previous step. The resulting aldehyde may then take two paths. It is either oxidized to a carboxylic acid or reduced to an alcohol , and then hydroxylated. Phase II metabolism consists of glucuronidation. The most prevalent metabolites in rats were 3-carboxymethylhydroxyamphetamine and 4-carboxymethylhydroxyamphetamine. Acute psychosis has been associated with recreational use of 6-APB in combination with the synthetic cannabinoid JWH Exposing compounds to the reagents gives a colour change which is indicative of the compound under test. The synthesis by Briner et al. The isomers were separated by silica gel column chromatography , then converted to their respective propanone derivatives, and then reductively aminated to give 6-APB and 4-APB, both of which were converted to their HCl ion pairs for further examination. In , a study funded by the Canadian Institutes of Health Research noted that 6-APB 'may or may not be legal in Canada depending on how one interprets the current Act' \\\\\\\\\\\\[12\\\\\\\\\\\\] and that it could be purchased for academic purposes without an exemption from Health Canada. Certain countries contain a 'substantially similar' catch-all clause in their drug law, such as New Zealand and Australia. From Wikipedia, the free encyclopedia. Empathogenic psychoactive compound of the substituted benzofuran, substituted amphetamine and substituted phenethylamine classes. IUPAC name. Interactive image. European Journal of Pharmacology. British Journal of Pharmacology. Journal of Psychopharmacology. Greene Boston: Academic Press. Drug and Alcohol Dependence. Journal of Medical Toxicology. Casale, Patrick A. Hays January Microgram Journal. Retrieved Drug Science, Policy and Law. Ministero della Salute. New Zealand Legislation. Amendment Order '. The National Archives. Substituted amphetamine Sub. PEA Sub. Diphenidine Ephenidine Fluorolintane Methoxphenidine. Dextrallorphan Dextromethorphan Dextrorphan Racemethorphan Racemorphan. Apomorphine Aporphine Bromocriptine Cabergoline Lisuride Memantine Nuciferine Pergolide Phenethylamine Piribedil Pramipexole Ropinirole Rotigotine Salvinorin A Also indirect D 2 agonists, such as dopamine reuptake inhibitors cocaine , methylphenidate , releasing agents amphetamine , methamphetamine , and precursors levodopa. Glaucine Isoaminile Noscapine Pukateine. Hidden categories: Webarchive template wayback links CS1 Italian-language sources it CS1 Swedish-language sources sv Articles with short description Articles with long short description Articles with changed CASNo identifier Articles without EBI source Chemical pages without DrugBank identifier Articles without KEGG source Drugboxes which contain changes to verified fields Drugboxes which contain changes to watched fields All articles with unsourced statements Articles with unsourced statements from January All articles lacking reliable references Articles lacking reliable references from November All articles with failed verification Articles with failed verification from June Namespaces Article Talk. Views Read Edit View history. In other projects Wikimedia Commons. By using this site, you agree to the Terms of Use and Privacy Policy.
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Benzo Fury 6 Apb Купить
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It is similar in structure to MDA , but differs in that the 3,4- methylenedioxyphenyl ring system has been replaced with a benzofuran ring. It may appear as a tan grainy powder. While the drug never became particularly popular, it briefly entered the rave and underground clubbing scene in the UK before its sale and import were banned. It falls under the category of research chemicals , sometimes called 'legal highs. The potent agonism of the 5-HT 2B receptor makes it likely that 6-APB would be cardiotoxic with chronic or long-term use, as seen with other 5-HT 2B receptor agonists such as the withdrawn serotonergic anorectic fenfluramine. The pharmacokinetics of 6-APB have not been studied, however, some information can be extracted from user reports. These suggest a slow onset of 40— minutes. The drugs peak effects last 7 hours, followed by a comedown phase of approximately 2 hours, and after effects for up to 24 hours. Although limited literature is available, there is some data on metabolism of 6-APB in rats. Its Phase I metabolism involves hydroxylation of the furan ring, then cleavage of the ring, followed by a reduction of the unsaturated aldehyde from the previous step. The resulting aldehyde may then take two paths. It is either oxidized to a carboxylic acid or reduced to an alcohol , and then hydroxylated. Phase II metabolism consists of glucuronidation. The most prevalent metabolites in rats were 3-carboxymethylhydroxyamphetamine and 4-carboxymethylhydroxyamphetamine. Acute psychosis has been associated with recreational use of 6-APB in combination with the synthetic cannabinoid JWH Exposing compounds to the reagents gives a colour change which is indicative of the compound under test. The synthesis by Briner et al. The isomers were separated by silica gel column chromatography , then converted to their respective propanone derivatives, and then reductively aminated to give 6-APB and 4-APB, both of which were converted to their HCl ion pairs for further examination. In , a study funded by the Canadian Institutes of Health Research noted that 6-APB 'may or may not be legal in Canada depending on how one interprets the current Act' \\\\\\\\\\\\\\[12\\\\\\\\\\\\\\] and that it could be purchased for academic purposes without an exemption from Health Canada. Certain countries contain a 'substantially similar' catch-all clause in their drug law, such as New Zealand and Australia. From Wikipedia, the free encyclopedia. Empathogenic psychoactive compound of the substituted benzofuran, substituted amphetamine and substituted phenethylamine classes. IUPAC name. Interactive image. European Journal of Pharmacology. British Journal of Pharmacology. Journal of Psychopharmacology. Greene Boston: Academic Press. Drug and Alcohol Dependence. Journal of Medical Toxicology. Casale, Patrick A. Hays January Microgram Journal. Retrieved Drug Science, Policy and Law. Ministero della Salute. New Zealand Legislation. Amendment Order '. The National Archives. Substituted amphetamine Sub. PEA Sub. Diphenidine Ephenidine Fluorolintane Methoxphenidine. Dextrallorphan Dextromethorphan Dextrorphan Racemethorphan Racemorphan. Apomorphine Aporphine Bromocriptine Cabergoline Lisuride Memantine Nuciferine Pergolide Phenethylamine Piribedil Pramipexole Ropinirole Rotigotine Salvinorin A Also indirect D 2 agonists, such as dopamine reuptake inhibitors cocaine , methylphenidate , releasing agents amphetamine , methamphetamine , and precursors levodopa. Glaucine Isoaminile Noscapine Pukateine. Hidden categories: Webarchive template wayback links CS1 Italian-language sources it CS1 Swedish-language sources sv Articles with short description Articles with long short description Articles with changed CASNo identifier Articles without EBI source Chemical pages without DrugBank identifier Articles without KEGG source Drugboxes which contain changes to verified fields Drugboxes which contain changes to watched fields All articles with unsourced statements Articles with unsourced statements from January All articles lacking reliable references Articles lacking reliable references from November All articles with failed verification Articles with failed verification from June Namespaces Article Talk. Views Read Edit View history. In other projects Wikimedia Commons. By using this site, you agree to the Terms of Use and Privacy Policy.
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