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It produces stimulant and entactogenic effects, and is described subjectively as being between amphetamine and MDMA. As a recreational drug , 4-FA is sometimes sold along with related compounds such as 2-fluoroamphetamine and 4-fluoromethamphetamine. The subjective effects of 4-fluoroamphetamine include euphoria which some find similar to the effects of MDMA and amphetamine, \\\\\\\\\\\\[3\\\\\\\\\\\\] increased energy stimulation , mood elevation, feelings of warmth and empathy, excessive talking, bruxism , and suppressed appetite anorexic. The general course of effects involves primarily empathogenic effects for the first few hours, which fades out as increased stimulation develops over the next several hours. Common acute side effects are nausea, headaches, increased heart rate and insomnia. Regarding the metabolic fate of 4-FA, the C-F bond at the 4-position on the phenyl ring likely resists deactivation in the liver by cytochrome P oxidase. Neurotoxicity does not increase down the series of para -halogenated amphetamine derivatives, even though serotonin releasing potency does follow this trend. For example, 4-iodoamphetamine is less toxic than is 4-chloroamphetamine. The extensive serotonergic neurotoxicity of 4-chloroamphetamine and its brominated derivative , and the increased serotonergic toxicity of 4-methylamphetamine \\\\\\\\\\\\[13\\\\\\\\\\\\] suggest that para-substitution seems to increase overall serotonergic neuro toxicity, compared to amphetamine. Exceptions include 4-MTA , a para -substituted, non-neurotoxic amphetamine. The LD 50 mouse; i. As of October , 4-FA is a controlled substance in China. From Wikipedia, the free encyclopedia. Anlage I Authorized scientific use only UK: Fc1ccc cc1 CC N C. European Journal of Pharmacology. Retrieved 14 February Annals of the New York Academy of Sciences. Drug levels in brain and effects on brain serotonin metabolism'. Pharmacology, Biochemistry, and Behavior. Journal of Pharmacology and Experimental Therapeutics. Journal of Psychopharmacology Oxford, England. The Journal of Pharmacology and Experimental Therapeutics. Amphetamines and Related Compounds. China Food and Drug Administration. Retrieved 1 October Retrieved 25 May Adapromine Amantadine Bromantane Memantine Rimantadine. Oxiracetam Phenylpiracetam Phenylpiracetam hydrazide. SoRI Adrenergic release blockers: Retrieved from ' https: Substituted amphetamines Entactogens and empathogens Fluoroarenes Designer drugs Serotonin-norepinephrine-dopamine releasing agents. Views Read Edit View history. This page was last edited on 18 October , at By using this site, you agree to the Terms of Use and Privacy Policy. Pale Blue \\\\\\\\\\\\[6\\\\\\\\\\\\] \\\\\\\\\\\\[7\\\\\\\\\\\\].

4fa